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  1. Content type: Original clinical investigation

    The number of patients treated with oral anticoagulation (OAC) is increasing and these patients are monitored by International Normalized Ratio (INR). Bleeding complications are common and we speculate if this...

    Authors: Sacha Sølbeck, Sisse R Ostrowski and Pär I Johansson

    Citation: Thrombosis Journal 2012 10:5

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  2. Content type: Case report

    A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein B...

    Authors: Suneth Karunarathne, Sajitha Weerasinghe, Dumitha Govindapala, Harshini Fernando and Bhaddika Jayaratne

    Citation: Thrombosis Journal 2012 10:4

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  3. Content type: Original clinical investigation

    Patients with heightened platelet reactivity in response to antiplatelet agents are at an increased risk of recurrent ischemic events. However, there is a lack of diagnostic criteria for increased response to ...

    Authors: Raul Altman, Ana J Rivas and Claudio D Gonzalez

    Citation: Thrombosis Journal 2012 10:3

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  4. Content type: Original basic research

    Stachybotrys microspora triprenyl phenols (SMTPs) are a novel family of small molecules that enhance both activation and fibrin-binding of plasminogen. While their effects on fibrinolysis have been characterized

    Authors: Weimin Hu, Ritsuko Narasaki, Naoko Nishimura and Keiji Hasumi

    Citation: Thrombosis Journal 2012 10:2

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  5. Content type: Original clinical investigation

    Effects of nitric oxide (NO) on hemostasis have been studied in various investigational settings, but data regarding inhaled NO on bleeding and platelet function are conflicting. It is not known if inhaled NO ...

    Authors: Brahm Goldstein, James Baldassarre and Joseph N Young

    Citation: Thrombosis Journal 2012 10:1

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  6. Content type: Original clinical investigation

    Venous thromboembolism prophylaxis has been shown to safely and cost-effectively reduce the incidence of thromboembolic events in medical inpatients. However, there is a gap between evidence and medical practi...

    Authors: Agustín Languasco, Mariana Galante, Josefina Marín, Cristina Soler, Cristián Lopez Saubidet and Matías Milberg

    Citation: Thrombosis Journal 2011 9:18

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  7. Content type: Review

    In European countries, low-molecular-weight heparin is generally initiated preoperatively for thromboprophylaxis in hip or knee replacement surgery. The objective of this review is to compare pre- and postoper...

    Authors: Carsten Perka

    Citation: Thrombosis Journal 2011 9:17

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  9. Content type: Original clinical investigation

    To assess the incidence of venous thromboembolism (VTE) and bleeding events with or without thromboprophylaxis and the associated costs in a cohort of medically ill patients in both in-hospital and outpatient ...

    Authors: Li Wang, Nishan Sengupta and Onur Baser

    Citation: Thrombosis Journal 2011 9:15

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  10. Content type: Original clinical investigation

    Patients who receive highly variable doses of warfarin may be at risk for poor anticoagulation control and adverse events. However, we lack a system to identify patients with the highest dose variability. Our ...

    Authors: Lyndonna Marrast, Mary Evans, Al Ozonoff, Lori E Henault and Adam J Rose

    Citation: Thrombosis Journal 2011 9:14

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  11. Content type: Case report

    The ergotamine tartrate associated with certain categories of drugs can lead to critical ischemia of the extremities. Discontinuation of taking ergotamine is usually sufficient for the total regression of isch...

    Authors: Edoardo Cervi, Stefano Bonardelli, Giuseppe Battaglia, Federico Gheza, Roberto Maffeis, Franco Nodari, Roberto Maroldi and Stefano M Giulini

    Citation: Thrombosis Journal 2011 9:13

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  14. Content type: Original clinical investigation

    Patients with vasospastic (VA) or non vasospastic angina (NVA) without significant coronary stenosis have a reduced risk of infarction but is unclear whether or not this may be attributable to a lack of prothr...

    Authors: Jaume Figueras, Jasone Monasterio, Enric Domingo, Beatriz Meneses, Elsa Nieto, Josefa Cortadellas and David Garcia-Dorado

    Citation: Thrombosis Journal 2011 9:10

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  16. Content type: Case report

    We report a case of near fatal aortic thrombosis in a trauma patient homozygous for mutation of Factor V Leiden. He responded well to vascular surgery and intensive care unit management and was discharged succ...

    Authors: Iraklis Tsangaris, Georgios Tsaknis, Argirios Tsantes, Petros Kopterides and Apostolos Armaganidis

    Citation: Thrombosis Journal 2011 9:8

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  17. Content type: Original clinical investigation

    Venous thromboembolism (VTE) is a major health and financial burden. VTE impacts health outcomes in surgical and non-surgical patients. VTE prophylaxis is underutilized, particularly amongst high risk medical ...

    Authors: Harry Gibbs, John Fletcher, Peter Blombery, Renea Collins and David Wheatley

    Citation: Thrombosis Journal 2011 9:7

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  18. Content type: Original basic research

    Mature carotid plaques are complex structures, and their histological classification is challenging. The carotid plaques of asymptomatic and symptomatic patients could exhibit identical histological components.

    Authors: Liz Andréa V Baroncini, Lia S Nakao, Simone G Ramos, Antonio Pazin Filho, Luiz Otávio Murta Jr, Max Ingberman, Cristiane Tefé-Silva and Dalton B Précoma

    Citation: Thrombosis Journal 2011 9:6

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  20. Content type: Original clinical investigation

    Different platelet function tests can be used to evaluate the degree of achieved platelet inhibition in patients treated with clopidogrel. The presence of CYP 2C19*2 polymorphism can reduce the formation of th...

    Authors: Alf-Aage R Pettersen, Harald Arnesen, Trine B Opstad and Ingebjorg Seljeflot

    Citation: Thrombosis Journal 2011 9:4

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  21. Content type: Original clinical investigation

    Patients undergoing elective total hip replacement (THR) surgery are at an increased risk for venous thromboembolic events (VTEs). Dalteparin and enoxaparin are recommended as thromboprophylaxis for at least 1...

    Authors: George Dranitsaris, Valentina Jelincic and Yoonhee Choe

    Citation: Thrombosis Journal 2011 9:3

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  22. Content type: Case report

    Recent literature reports an increased incidence of venous thrombosis following thalidomide use in the treatment of diseases with disease-related thrombotic risks such as malignancy, as well as concomitant use...

    Authors: Riyaaz Ahamed, Wijesiriwardena Bandula and Ratnayake Chamara

    Citation: Thrombosis Journal 2011 9:2

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  23. Content type: Original clinical investigation

    Cirrhotic patients are characterized by a decreased synthesis of coagulation and anticoagulation factors. The coagulopathy of cirrhotic patients is considered to be auto-anticoagulation. Our aim was to determi...

    Authors: Abdulaziz Aldawood, Yaseen Arabi, Abdulrahman Aljumah, Alawi Alsaeedi, Asgar Rishu, Hasan Aldorzi, Saad Alqahtani, Mohammad Alsultan and Afaf Felemban

    Citation: Thrombosis Journal 2011 9:1

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  24. Content type: Original clinical investigation

    Patients with gynecologic cancer have a high risk of venous thromboembolism (VTE) like patients with other cancers. However, there is little information on risk factors for VTE during gynecologic surgery and n...

    Authors: Nao Suzuki, Norihito Yoshioka, Tatsuru Ohara, Noriyuki Yokomichi, Takafumi Nako, Namiko Yahagi, Suguru Igarashi, Yoichi Kobayashi, Misako Yoshimatsu, Kenji Takizawa, Yasuo Nakajima, Kazushige Kiguchi and Bunpei Ishizuka

    Citation: Thrombosis Journal 2010 8:17

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  25. Content type: Original clinical investigation

    Periodontitis is associated with cardiovascular diseases (CVD). In our previous studies a prothrombotic state has been observed in periodontitis, which contributes to the risk of CVD. The aim of this study was...

    Authors: Sergio Bizzarro, Elena A Nicu, Ubele van der Velden, Marja L Laine and Bruno G Loos

    Citation: Thrombosis Journal 2010 8:16

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  26. Content type: Original clinical investigation

    Left ventricular thrombus(LVT] formation is a frequent complication in patients with acute anterior myocardial infarction(MI). LVT is associated with increased risk of embolism and higher mortality rates after...

    Authors: Ertuğrul Okuyan, Barış Okcun, Mustafa H Dinçkal and Haşim Mutlu

    Citation: Thrombosis Journal 2010 8:15

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  27. Content type: Original basic research

    The chemokine receptors CCR2 and CX3CR1 are important in the development of coronary artery disease. The purpose of this study is to analyze the effect of a novel CCR2 inhibitor in conjunction with CX3CR1 dele...

    Authors: Maya R Jerath, Peng Liu, Mary Struthers, Julie A DeMartino, Roche Peng, Laurence B Peterson, Anne-Marie Cumiskey, Lihu Yang, Mauricio Rojas, Dhavalkumar D Patel and Alan M Fong

    Citation: Thrombosis Journal 2010 8:14

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  28. Content type: Case report

    Beta-lactam antibiotics, e.g. penicillin, may inhibit platelet function and lead to reduced response in light transmission aggregometry and adhesion. However, influence on platelet function tests more commonly...

    Authors: Christian Schulz, Olga von Beckerath, Rainer Okrojek, Nicolas von Beckerath and Steffen Massberg

    Citation: Thrombosis Journal 2010 8:13

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  29. Content type: Case report

    Normal pregnancy corresponds to a procoagulant state. Acute myocardial infarction during pregnancy is rare, yet considering the low non-pregnant risk score of childbearing women it is still surprisingly freque...

    Authors: Spyridon Arampatzis, Ioannis Stefanidis, Vassilios Liakopoulos, Luigi Raio, Daniel Surbek and Markus G Mohaupt

    Citation: Thrombosis Journal 2010 8:12

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  30. Content type: Original basic research

    Information on hemostasis and platelet function in brown bear (Ursus arctos) is of importance for understanding the physiological, protective changes during hibernation.

    Authors: Ole Fröbert, Kjeld Christensen, Åsa Fahlman, Sven Brunberg, Johan Josefsson, Eva Särndahl, Jon E Swenson and Jon M Arnemo

    Citation: Thrombosis Journal 2010 8:11

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  31. Content type: Original clinical investigation

    Protein C (PC) and protein S (PS) determination is part of the thrombophilia investigation in patients with idiopathic venous thromboembolism (VTE). Based on scarce evidence it is a common notion that PC and P...

    Authors: Leonard Minuk, Alejandro Lazo-Langner, Judy Kovacs, Melinda Robbins, Bev Morrow and Michael Kovacs

    Citation: Thrombosis Journal 2010 8:10

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  32. Content type: Original basic research

    Poor platelet inhibition by aspirin or clopidogrel has been associated with adverse outcomes in patients with cardiovascular diseases. A reliable and facile assay to measure platelet inhibition after treatment...

    Authors: Sandra M Penz, Isabell Bernlochner, Orsolya Tóth, Reinhard Lorenz, Andreas Calatzis and Wolfgang Siess

    Citation: Thrombosis Journal 2010 8:9

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  33. Content type: Latest therapeutic developments

    High concentrations of recombinant activated factor VII (rFVIIa) can stop bleeding in hemophilic patients. However the rFVIIa dose needed for stopping haemhorrage in off-label indications is unknown. Since thr...

    Authors: Raul Altman, Alejandra Scazziota, Maria de Lourdes Herrera and Claudio D Gonzalez

    Citation: Thrombosis Journal 2010 8:8

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  34. Content type: Original clinical investigation

    Tissue factor (TF) and its inhibitor tissue factor pathway inhibitor (TFPI) are the main regulators of the initiation of the coagulation process, important in atherothrombosis. In this study we have investigat...

    Authors: Trine B Opstad, Alf Åge Pettersen, Thomas Weiss, Harald Arnesen and Ingebjørg Seljeflot

    Citation: Thrombosis Journal 2010 8:7

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  35. Content type: Original clinical investigation

    The pathophysiological pathways resulting in Late Stent Thrombosis (LST) remain uncertain. Findings from animal studies indicate a role of the intrinsic coagulation pathway in arterial thrombus formation, whil...

    Authors: Volker Pönitz, José W Govers-Riemslag, Hugo ten Cate, Rene van Oerle, Trygve Brügger-Andersen, Heidi Grundt, Patrycja Næsgaard, David Pritchard, Alf I Larsen and Dennis W Nilsen

    Citation: Thrombosis Journal 2010 8:6

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  36. Content type: Original clinical investigation

    Despite the high frequency with which adverse drug events (ADEs) occur in outpatient settings, detailed information regarding these events remains limited. Anticoagulant drugs are associated with increased saf...

    Authors: Andrea L Long, Lisa Bendz, Monica M Horvath, Heidi Cozart, Julie Eckstrand, Julie Whitehurst and Jeffrey Ferranti

    Citation: Thrombosis Journal 2010 8:5

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  37. Content type: Original clinical investigation

    Postoperative asymptomatic deep venous thromboses (ADVT) can give rise to posttthrombotic syndrome (PTS), but there are still many unresolved issues in this context. For example, there is a lack of knowledge r...

    Authors: Stefan Rosfors, Lena M Persson, Gerd Lärfars and Lasse J Lapidus

    Citation: Thrombosis Journal 2010 8:4

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  38. Content type: Original basic research

    Experimental models of pulmonary embolism (PE) that produce pulmonary hypertension (PH) employ many different methods of inducing acute pulmonary occlusion. Many of these models induce PE with intravenous inje...

    Authors: Michael S Runyon, Michael A Gellar, Nina Sanapareddy, Jeffrey A Kline and John A Watts

    Citation: Thrombosis Journal 2010 8:3

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  39. Content type: Original basic research

    Interaction of fibrinogen with specific leukocyte integrins of monocytes may link coagulation and inflammation, however, the precise mechanism of fibrinogen leading to the pro-inflammatory and pro-coagulatory ...

    Authors: Nicole C Kaneider, Birgit Mosheimer, Andrea Günther, Clemens Feistritzer and Christian J Wiedermann

    Citation: Thrombosis Journal 2010 8:2

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  40. Content type: Original clinical investigation

    The expression of pregnancy-associated plasma protein A (PAPP-A) was identified by immunohistochemistry (IHC) in culprit atherothrombotic plaque specimens harvested from patients admitted with ST-segment eleva...

    Authors: Trygve Brügger-Andersen, Leif Bostad, Dagny Ann Sandnes, AlfInge Larsen, Vernon VS Bonarjee, Ståle Barvik, Tor Melberg and Dennis WT Nilsen

    Citation: Thrombosis Journal 2010 8:1

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  41. Content type: Latest therapeutic developments

    Hemostasis is a defense mechanism to stop bleeding. Activated by vessel wall injury, it consists of intertwined activation of platelets and the coagulation cascade, tightly controlled by natural anticoagulants...

    Authors: Peter Verhamme and Marc F Hoylaerts

    Citation: Thrombosis Journal 2009 7:15

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  42. Content type: Original basic research

    Low molecular weight heparin (LMWH) is in vast usage for treatment of thromboembolic diseases such as deep venous thrombosis and acute coronary syndromes. There are certain clinical situations where a quick po...

    Authors: Ramin Artang, Niels J Frandsen and Jørn Dalsgaard Nielsen

    Citation: Thrombosis Journal 2009 7:14

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  43. Content type: Original basic research

    Myocardial infarction is the combined result of environmental factors and personal predispositions. Prothrombotic factors might play an important role in this phenomenon. Annexin V (ANV) is a calcium-dependent...

    Authors: Mohammad Shojaie, Abdoreza Sotoodah, Shohre Roozmeh, Ensieh Kholoosi and Samira Dana

    Citation: Thrombosis Journal 2009 7:13

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  44. Content type: Original clinical investigation

    Recurrent cardiovascular events following acute myocardial infarction (AMI) are common. The purpose of this study was to evaluate the impact of platelet aggregation, PFA-100 closure times and peak C-reactive p...

    Authors: Angelo Modica, Fredrik Karlsson and Thomas Mooe

    Citation: Thrombosis Journal 2009 7:12

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  45. Content type: Original clinical investigation

    Tissue factor (TF) contributes to thrombosis following plaque disruption in acute coronary syndromes (ACS). Aim of the study was to investigate the impact of plasma TF activity on prognosis in patients with ACS.

    Authors: Birgit A Steppich, Siegmund Lorenz Braun, Andreas Stein, Gabriele Demetz, Philip Groha, Albert Schömig, Nicolas von Beckerath, Adnan Kastrati and Ilka Ott

    Citation: Thrombosis Journal 2009 7:11

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  46. Content type: Original clinical investigation

    Endothelial cell dysfunction, by promoting fibrin deposition, has been implicated in the development of multiple organ failure. Altered fibrinolysis during inflammation may participate in microvascular alterat...

    Authors: Karim Zouaoui Boudjeltia, Sandra Ollieuz, Michael Piagnerelli, Patrick Biston, Philippe Cauchie, Jean-Louis Vincent, Dany Brohee and Michel Vanhaeverbeek

    Citation: Thrombosis Journal 2009 7:10

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  47. Content type: Original basic research

    The Azorean population presents the highest standardized mortality rate for cardiovascular diseases (CVD) when compared to mainland Portugal and other populations. Since thrombosis is a common cause of CVD, we...

    Authors: Claudia C Branco, Tânia Pereirinha, Rita Cabral, Paula R Pacheco and Luisa Mota-Vieira

    Citation: Thrombosis Journal 2009 7:9

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  48. Content type: Case report

    The aim of this case report is to describe control of Schamberg's disease using aminaphtone. We report on the case of a 28-year-old patient who presented with multiple purpuric lesions of the lower extremities...

    Authors: José Maria Pereira de Godoy and Fernando Batigália

    Citation: Thrombosis Journal 2009 7:8

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  50. Content type: Case report

    Every year, millions of people undergo percutaneous coronary intervention (PCI) with intracoronary stent implantation. A patient from the PRAGUE-8 trial (Optimal pre-PCI clopidogrel loading: 600 mg before ever...

    Authors: Zuzana Motovska, Petr Widimsky, Iuri Marinov, Robert Petr, Jaroslava Hajkova and Jan Kvasnicka

    Citation: Thrombosis Journal 2009 7:6

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