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  1. Postprandial hyperlipidemia and hyperglycemia have been related to cardiovascular events. Among different underlying mechanisms platelet activation seems to be responsible too. No comparable data between vario...

    Authors: Helmut Sinzinger and Robert Berent

    Citation: Thrombosis Journal 2012 10:19

    Content type: Review

    Published on:

  3. Computer-assistance and self-monitoring lower the cost and may improve the quality of anticoagulation therapy. The main purpose of this clinical investigation was to use computer-assisted oral anticoagulant th...

    Authors: Rune Skovgaard Rasmussen, Pernille Corell, Poul Madsen and Karsten Overgaard

    Citation: Thrombosis Journal 2012 10:17

    Content type: Original clinical investigation

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  4. Coronary artery disease (CAD) is a major problem worldwide. Atherosclerosis and thrombosis underlying CAD involve multiple cell types. New and useful diagnostic markers are required. MicroRNAs (miRNAs) are a c...

    Authors: Xiao Sun, Man Zhang, Akimasa Sanagawa, Chieko Mori, Shiori Ito, Soichiro Iwaki, Hiroki Satoh and Satoshi Fujii

    Citation: Thrombosis Journal 2012 10:16

    Content type: Original clinical investigation

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  5. Bleeding remains a potentially lethal complication of cardio-pulmonary bypass (CPB) surgery. The purpose of this study was to obtain a better insight into in vitro thrombin generation in the context of CPB.

    Authors: Rose Said, Véronique Regnault, Marie Hacquard, Jean-Pierre Carteaux and Thomas Lecompte

    Citation: Thrombosis Journal 2012 10:15

    Content type: Original clinical investigation

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  6. Venous Thrombo-embolic disease is currently a hot topic especially in the UK. 25,000 patients per year die of Pulmonary Emboli (PE) in the United Kingdom (UK). Hip and knee arthroplasty surgery is associated w...

    Authors: Padmanabhan Subramanian, Shanjitha Kantharuban, Sophie Shilston and Oliver James Pearce

    Citation: Thrombosis Journal 2012 10:14

    Content type: Original basic research

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  7. Obesity, characterised by increased fat mass and is currently regarded as a pro-inflammatory state and often associated with increased risk of cardiovascular diseases (CVD) including Myocardial infarction. The...

    Authors: Karthick Rajendran, Nalini Devarajan, Manohar Ganesan and Malathi Ragunathan

    Citation: Thrombosis Journal 2012 10:13

    Content type: Original basic research

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  8. Cardiovascular disease with disturbances in the haemostatic system, might lead to thrombotic complications with clinical manifestations like acute myocardial infarction (AMI) and stroke. Activation of the coag...

    Authors: Vibeke Bratseth, Alf-Åge Pettersen, Trine B Opstad, Harald Arnesen and Ingebjørg Seljeflot

    Citation: Thrombosis Journal 2012 10:12

    Content type: Original clinical investigation

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  9. Arterial thrombosis triggered by vascular injury is a balance between thrombus growth and thrombus fragmentation (dethrombosis). Unbalance towards thrombus growth can lead to vascular occlusion, downstream isc...

    Authors: Gillian Stephens, Ming He, Connie Wong, Marzena Jurek, Hans-Christian Luedemann, Golnaz Shapurian, Kevin Munnelly, Craig Muir, Pamela B Conley, David R Phillips and Patrick Andre

    Citation: Thrombosis Journal 2012 10:11

    Content type: Original basic research

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  10. The aim was to investigate, whether 5,000 IUaXa/day certoparin lowers the incidence of deep vein thrombosis (DVT) in patients undergoing elective hip replacement surgery vs. 3,000 IUaXa/day. Double-blind, multice...

    Authors: Peter Bramlage, Hans-Christoph Michaelis and Nima Melzer

    Citation: Thrombosis Journal 2012 10:10

    Content type: Original clinical investigation

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  11. There has been a shift towards greater use of neuraxial over general anaesthesia for patients undergoing total hip or knee arthroplasty. Furthermore, suggestions that peripheral nerve block may reduce adverse ...

    Authors: Nadia Rosencher, Herbert Noack, Martin Feuring, Andreas Clemens, Richard J Friedman and Bengt I Eriksson

    Citation: Thrombosis Journal 2012 10:9

    Content type: Original clinical investigation

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  12. Thrombosis and hemostasis related disease have a heavy burden in cardiovascular disease and it is important to have a journal where research into this can be accessed by all.

    Authors: Hugo ten Cate and Yukio Ozaki

    Citation: Thrombosis Journal 2012 10:8

    Content type: Editorial

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  13. DVT is the main cause of death in hospitalized patients and thromboprophylaxis is the only way to prevent these deaths. International recommendations suggested that active monitoring of DVT/PE prophylaxis can ...

    Authors: Federico Jorge Bottaro, José Manuel Ceresetto, John Emery, Julio Bruetman, Nicholas Emery, Débora Pellegrini, Victoria Pinoni, Gastón Piñeiro, Laura Fox, María Eugenia Orrico, Silvina Palmer, Sebastián Prieto and Eduardo Bullorsky

    Citation: Thrombosis Journal 2012 10:7

    Content type: Original clinical investigation

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  14. The clinical use of Sodium nitroprusside (SNP) may be associated with an alteration of platelet function. The main focus of this study was the effect of SNP on platelet aggregation in the absence or presence o...

    Authors: Hans-Georg Topf, Manfred Rauh, Wolfgang Rascher, Jörg Dötsch and Jens M Klinge

    Citation: Thrombosis Journal 2012 10:6

    Content type: Original basic research

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  15. The number of patients treated with oral anticoagulation (OAC) is increasing and these patients are monitored by International Normalized Ratio (INR). Bleeding complications are common and we speculate if this...

    Authors: Sacha Sølbeck, Sisse R Ostrowski and Pär I Johansson

    Citation: Thrombosis Journal 2012 10:5

    Content type: Original clinical investigation

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  16. A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein B...

    Authors: Suneth Karunarathne, Sajitha Weerasinghe, Dumitha Govindapala, Harshini Fernando and Bhaddika Jayaratne

    Citation: Thrombosis Journal 2012 10:4

    Content type: Case report

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  17. Patients with heightened platelet reactivity in response to antiplatelet agents are at an increased risk of recurrent ischemic events. However, there is a lack of diagnostic criteria for increased response to ...

    Authors: Raul Altman, Ana J Rivas and Claudio D Gonzalez

    Citation: Thrombosis Journal 2012 10:3

    Content type: Original clinical investigation

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  18. Stachybotrys microspora triprenyl phenols (SMTPs) are a novel family of small molecules that enhance both activation and fibrin-binding of plasminogen. While their effects on fibrinolysis have been characterized

    Authors: Weimin Hu, Ritsuko Narasaki, Naoko Nishimura and Keiji Hasumi

    Citation: Thrombosis Journal 2012 10:2

    Content type: Original basic research

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  19. Effects of nitric oxide (NO) on hemostasis have been studied in various investigational settings, but data regarding inhaled NO on bleeding and platelet function are conflicting. It is not known if inhaled NO ...

    Authors: Brahm Goldstein, James Baldassarre and Joseph N Young

    Citation: Thrombosis Journal 2012 10:1

    Content type: Original clinical investigation

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  20. Venous thromboembolism prophylaxis has been shown to safely and cost-effectively reduce the incidence of thromboembolic events in medical inpatients. However, there is a gap between evidence and medical practi...

    Authors: Agustín Languasco, Mariana Galante, Josefina Marín, Cristina Soler, Cristián Lopez Saubidet and Matías Milberg

    Citation: Thrombosis Journal 2011 9:18

    Content type: Original clinical investigation

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  21. In European countries, low-molecular-weight heparin is generally initiated preoperatively for thromboprophylaxis in hip or knee replacement surgery. The objective of this review is to compare pre- and postoper...

    Authors: Carsten Perka

    Citation: Thrombosis Journal 2011 9:17

    Content type: Review

    Published on:

  23. To assess the incidence of venous thromboembolism (VTE) and bleeding events with or without thromboprophylaxis and the associated costs in a cohort of medically ill patients in both in-hospital and outpatient ...

    Authors: Li Wang, Nishan Sengupta and Onur Baser

    Citation: Thrombosis Journal 2011 9:15

    Content type: Original clinical investigation

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  24. Patients who receive highly variable doses of warfarin may be at risk for poor anticoagulation control and adverse events. However, we lack a system to identify patients with the highest dose variability. Our ...

    Authors: Lyndonna Marrast, Mary Evans, Al Ozonoff, Lori E Henault and Adam J Rose

    Citation: Thrombosis Journal 2011 9:14

    Content type: Original clinical investigation

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  25. The ergotamine tartrate associated with certain categories of drugs can lead to critical ischemia of the extremities. Discontinuation of taking ergotamine is usually sufficient for the total regression of isch...

    Authors: Edoardo Cervi, Stefano Bonardelli, Giuseppe Battaglia, Federico Gheza, Roberto Maffeis, Franco Nodari, Roberto Maroldi and Stefano M Giulini

    Citation: Thrombosis Journal 2011 9:13

    Content type: Case report

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  28. Patients with vasospastic (VA) or non vasospastic angina (NVA) without significant coronary stenosis have a reduced risk of infarction but is unclear whether or not this may be attributable to a lack of prothr...

    Authors: Jaume Figueras, Jasone Monasterio, Enric Domingo, Beatriz Meneses, Elsa Nieto, Josefa Cortadellas and David Garcia-Dorado

    Citation: Thrombosis Journal 2011 9:10

    Content type: Original clinical investigation

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  30. We report a case of near fatal aortic thrombosis in a trauma patient homozygous for mutation of Factor V Leiden. He responded well to vascular surgery and intensive care unit management and was discharged succ...

    Authors: Iraklis Tsangaris, Georgios Tsaknis, Argirios Tsantes, Petros Kopterides and Apostolos Armaganidis

    Citation: Thrombosis Journal 2011 9:8

    Content type: Case report

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  31. Venous thromboembolism (VTE) is a major health and financial burden. VTE impacts health outcomes in surgical and non-surgical patients. VTE prophylaxis is underutilized, particularly amongst high risk medical ...

    Authors: Harry Gibbs, John Fletcher, Peter Blombery, Renea Collins and David Wheatley

    Citation: Thrombosis Journal 2011 9:7

    Content type: Original clinical investigation

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  32. Mature carotid plaques are complex structures, and their histological classification is challenging. The carotid plaques of asymptomatic and symptomatic patients could exhibit identical histological components.

    Authors: Liz Andréa V Baroncini, Lia S Nakao, Simone G Ramos, Antonio Pazin Filho, Luiz Otávio Murta Jr, Max Ingberman, Cristiane Tefé-Silva and Dalton B Précoma

    Citation: Thrombosis Journal 2011 9:6

    Content type: Original basic research

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  34. Different platelet function tests can be used to evaluate the degree of achieved platelet inhibition in patients treated with clopidogrel. The presence of CYP 2C19*2 polymorphism can reduce the formation of th...

    Authors: Alf-Aage R Pettersen, Harald Arnesen, Trine B Opstad and Ingebjorg Seljeflot

    Citation: Thrombosis Journal 2011 9:4

    Content type: Original clinical investigation

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  35. Patients undergoing elective total hip replacement (THR) surgery are at an increased risk for venous thromboembolic events (VTEs). Dalteparin and enoxaparin are recommended as thromboprophylaxis for at least 1...

    Authors: George Dranitsaris, Valentina Jelincic and Yoonhee Choe

    Citation: Thrombosis Journal 2011 9:3

    Content type: Original clinical investigation

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  36. Recent literature reports an increased incidence of venous thrombosis following thalidomide use in the treatment of diseases with disease-related thrombotic risks such as malignancy, as well as concomitant use...

    Authors: Riyaaz Ahamed, Wijesiriwardena Bandula and Ratnayake Chamara

    Citation: Thrombosis Journal 2011 9:2

    Content type: Case report

    Published on:

  37. Cirrhotic patients are characterized by a decreased synthesis of coagulation and anticoagulation factors. The coagulopathy of cirrhotic patients is considered to be auto-anticoagulation. Our aim was to determi...

    Authors: Abdulaziz Aldawood, Yaseen Arabi, Abdulrahman Aljumah, Alawi Alsaeedi, Asgar Rishu, Hasan Aldorzi, Saad Alqahtani, Mohammad Alsultan and Afaf Felemban

    Citation: Thrombosis Journal 2011 9:1

    Content type: Original clinical investigation

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  38. Patients with gynecologic cancer have a high risk of venous thromboembolism (VTE) like patients with other cancers. However, there is little information on risk factors for VTE during gynecologic surgery and n...

    Authors: Nao Suzuki, Norihito Yoshioka, Tatsuru Ohara, Noriyuki Yokomichi, Takafumi Nako, Namiko Yahagi, Suguru Igarashi, Yoichi Kobayashi, Misako Yoshimatsu, Kenji Takizawa, Yasuo Nakajima, Kazushige Kiguchi and Bunpei Ishizuka

    Citation: Thrombosis Journal 2010 8:17

    Content type: Original clinical investigation

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  39. Periodontitis is associated with cardiovascular diseases (CVD). In our previous studies a prothrombotic state has been observed in periodontitis, which contributes to the risk of CVD. The aim of this study was...

    Authors: Sergio Bizzarro, Elena A Nicu, Ubele van der Velden, Marja L Laine and Bruno G Loos

    Citation: Thrombosis Journal 2010 8:16

    Content type: Original clinical investigation

    Published on:

  40. Left ventricular thrombus(LVT] formation is a frequent complication in patients with acute anterior myocardial infarction(MI). LVT is associated with increased risk of embolism and higher mortality rates after...

    Authors: Ertuğrul Okuyan, Barış Okcun, Mustafa H Dinçkal and Haşim Mutlu

    Citation: Thrombosis Journal 2010 8:15

    Content type: Original clinical investigation

    Published on:

  41. The chemokine receptors CCR2 and CX3CR1 are important in the development of coronary artery disease. The purpose of this study is to analyze the effect of a novel CCR2 inhibitor in conjunction with CX3CR1 dele...

    Authors: Maya R Jerath, Peng Liu, Mary Struthers, Julie A DeMartino, Roche Peng, Laurence B Peterson, Anne-Marie Cumiskey, Lihu Yang, Mauricio Rojas, Dhavalkumar D Patel and Alan M Fong

    Citation: Thrombosis Journal 2010 8:14

    Content type: Original basic research

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  42. Beta-lactam antibiotics, e.g. penicillin, may inhibit platelet function and lead to reduced response in light transmission aggregometry and adhesion. However, influence on platelet function tests more commonly...

    Authors: Christian Schulz, Olga von Beckerath, Rainer Okrojek, Nicolas von Beckerath and Steffen Massberg

    Citation: Thrombosis Journal 2010 8:13

    Content type: Case report

    Published on:

  43. Normal pregnancy corresponds to a procoagulant state. Acute myocardial infarction during pregnancy is rare, yet considering the low non-pregnant risk score of childbearing women it is still surprisingly freque...

    Authors: Spyridon Arampatzis, Ioannis Stefanidis, Vassilios Liakopoulos, Luigi Raio, Daniel Surbek and Markus G Mohaupt

    Citation: Thrombosis Journal 2010 8:12

    Content type: Case report

    Published on:

  44. Information on hemostasis and platelet function in brown bear (Ursus arctos) is of importance for understanding the physiological, protective changes during hibernation.

    Authors: Ole Fröbert, Kjeld Christensen, Åsa Fahlman, Sven Brunberg, Johan Josefsson, Eva Särndahl, Jon E Swenson and Jon M Arnemo

    Citation: Thrombosis Journal 2010 8:11

    Content type: Original basic research

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  45. Protein C (PC) and protein S (PS) determination is part of the thrombophilia investigation in patients with idiopathic venous thromboembolism (VTE). Based on scarce evidence it is a common notion that PC and P...

    Authors: Leonard Minuk, Alejandro Lazo-Langner, Judy Kovacs, Melinda Robbins, Bev Morrow and Michael Kovacs

    Citation: Thrombosis Journal 2010 8:10

    Content type: Original clinical investigation

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  46. Poor platelet inhibition by aspirin or clopidogrel has been associated with adverse outcomes in patients with cardiovascular diseases. A reliable and facile assay to measure platelet inhibition after treatment...

    Authors: Sandra M Penz, Isabell Bernlochner, Orsolya Tóth, Reinhard Lorenz, Andreas Calatzis and Wolfgang Siess

    Citation: Thrombosis Journal 2010 8:9

    Content type: Original basic research

    Published on:

  47. High concentrations of recombinant activated factor VII (rFVIIa) can stop bleeding in hemophilic patients. However the rFVIIa dose needed for stopping haemhorrage in off-label indications is unknown. Since thr...

    Authors: Raul Altman, Alejandra Scazziota, Maria de Lourdes Herrera and Claudio D Gonzalez

    Citation: Thrombosis Journal 2010 8:8

    Content type: Latest therapeutic developments

    Published on:

  48. Tissue factor (TF) and its inhibitor tissue factor pathway inhibitor (TFPI) are the main regulators of the initiation of the coagulation process, important in atherothrombosis. In this study we have investigat...

    Authors: Trine B Opstad, Alf Åge Pettersen, Thomas Weiss, Harald Arnesen and Ingebjørg Seljeflot

    Citation: Thrombosis Journal 2010 8:7

    Content type: Original clinical investigation

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  49. The pathophysiological pathways resulting in Late Stent Thrombosis (LST) remain uncertain. Findings from animal studies indicate a role of the intrinsic coagulation pathway in arterial thrombus formation, whil...

    Authors: Volker Pönitz, José W Govers-Riemslag, Hugo ten Cate, Rene van Oerle, Trygve Brügger-Andersen, Heidi Grundt, Patrycja Næsgaard, David Pritchard, Alf I Larsen and Dennis W Nilsen

    Citation: Thrombosis Journal 2010 8:6

    Content type: Original clinical investigation

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  50. Despite the high frequency with which adverse drug events (ADEs) occur in outpatient settings, detailed information regarding these events remains limited. Anticoagulant drugs are associated with increased saf...

    Authors: Andrea L Long, Lisa Bendz, Monica M Horvath, Heidi Cozart, Julie Eckstrand, Julie Whitehurst and Jeffrey Ferranti

    Citation: Thrombosis Journal 2010 8:5

    Content type: Original clinical investigation

    Published on:

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