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  1. Thrombosis plays an important role in the Coronavrus Disease 2019 (COVID-19) infection-related complications such as acute respiratory distress syndrome and myocardial infarction. Multiple factors such as oxyg...

    Authors: Mahin Behzadi Fard, Samaneh Behzadi Fard, Shahin Ramazi, Amir Atashi and Zahra Eslamifar
    Citation: Thrombosis Journal 2021 19:59
    Content type: Review Published on:

  2. Previous studies have shown conflicting results regarding the influence of cardiovascular risk-factors on venous thromboembolism. This study aimed to determine if these risk-factors, i.e. physical activity, sm...

    Authors: C. J. MacDonald, A. L. Madika, M. Lajous, M. Canonico, A. Fournier and M. C. Boutron-Ruault
    Citation: Thrombosis Journal 2021 19:58
    Content type: Research Published on:

  3. The coronavirus disease (COVID-19) pandemic has led to an unprecedented worldwide burden of disease. However, little is known of the longer-term implications and consequences of COVID-19. One of these may be a...

    Authors: Rajiv Advani, Torbjørn Austveg Strømsnes, Espen Stjernstrøm and Sebastian T. Lugg
    Citation: Thrombosis Journal 2021 19:57
    Content type: Case report Published on:

  5. Coronavirus disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure is associated with high mortality. The pathogenesis of COVID-19 is associated with microembolism or microvascular endo...

    Authors: Fumihiro Ogawa, Yasufumi Oi, Kento Nakajima, Reo Matsumura, Tomoki Nakagawa, Takao Miyagawa, Kazuya Sakai, Ryo Saji, Hayato Taniguchi, Kohei Takahashi, Takeru Abe, Masayuki Iwashita, Mototsugu Nishii and Ichiro Takeuchi
    Citation: Thrombosis Journal 2021 19:55
    Content type: Research Published on:

  6. We review the evidence for tranexamic acid (TXA) for the treatment and prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight therapeutic areas where evidence is lacking and disc...

    Authors: Anna Ockerman, Thomas Vanassche, Melisa Garip, Christophe Vandenbriele, Matthias M Engelen, Jeroen Martens, Constantinus Politis, Reinhilde Jacobs and Peter Verhamme
    Citation: Thrombosis Journal 2021 19:54
    Content type: Review Published on:

  7. Data are limited on patient background characteristics associated with catheter ablation (CA)-related bleeding events in Japanese patients with non-valvular atrial fibrillation receiving uninterrupted periproc...

    Authors: Ichitaro Abe, Naohiko Takahashi, Yasushi Mukai, Tetsuya Kimura, Keita Yamaguchi, Atsushi Takita, Hideki Origasa and Ken Okumura
    Citation: Thrombosis Journal 2021 19:53
    Content type: Research Published on:

  12. Phlebitis, inflammation of tunica intima of venous wall, occurred in 13–56% of hospitalized patients. It is characterized by pain, erythema, swelling, palpable venous cord, and pussy discharge at catheter site...

    Authors: Mulugeta Lulie, Abilo Tadesse, Tewodros Tsegaye, Tesfaye Yesuf and Mezgebu Silamsaw
    Citation: Thrombosis Journal 2021 19:48
    Content type: Research Published on:

  15. Statins are a potential treatment for venous thromboembolism (VTE) prophylaxis complementary to conventional anticoagulants without associated bleeding complications. This study aimed to compare pro-thrombotic...

    Authors: Mohammadreza Bordbar, Renée de Mutsert, Melike Cevval, Frits R. Rosendaal, J. Wouter Jukema and Willem M. Lijfering
    Citation: Thrombosis Journal 2021 19:45
    Content type: Research Published on:

  16. Although the rate of childhood acute lymphoblastic leukemia (ALL) is increasing in Africa, there is a dearth of information on the disease and the dynamics of hemostatic parameters with therapy.

    Authors: William Osei-OWusu, David Ofosu Ntiamoah, Gordon Asare Akuffo, Selina Mintaah, Michael Owusu, Benedict Sackey, Lilian Antwi-Boateng, Ganiwu Abdul, Max Annani-Akollor, Eddie-Williams Owiredu, Alexander Yaw Debrah and Otchere Addai-Mensah
    Citation: Thrombosis Journal 2021 19:44
    Content type: Research Published on:

  21. Coronavirus disease 2019 (COVID-19) associated coagulopathy (CAC) leads to thromboembolic events in a high number of critically ill COVID-19 patients. However, specific diagnostic or therapeutic algorithms for...

    Authors: Johannes Herrmann, Quirin Notz, Tobias Schlesinger, Jan Stumpner, Markus Kredel, Magdalena Sitter, Benedikt Schmid, Peter Kranke, Harald Schulze, Patrick Meybohm and Christopher Lotz
    Citation: Thrombosis Journal 2021 19:39
    Content type: Research Published on:

  22. Deep vein thrombosis (DVT) is common in critically ill patients with Coronavirus disease 2019 (COVID-19) and may cause fatal pulmonary embolism (PE) prior to diagnosis due to subtle clinical symptoms. The aim ...

    Authors: Sarah Galien, Michael Hultström, Miklós Lipcsey, Karl Stattin, Robert Frithiof and Jacob Rosén
    Citation: Thrombosis Journal 2021 19:38
    Content type: Research Published on:

  23. There is a need for clinical outcome data of cerebral venous thrombosis (CVT) in cancer patients. We examined the recanalization, thrombosis recurrence and major bleeding during CVT treatment in a cancer exclu...

    Authors: Nadia I Abelhad, Wei Qiao, Naveen Garg and Cristhiam M. Rojas-Hernandez
    Citation: Thrombosis Journal 2021 19:37
    Content type: Research Published on:

    The Correction to this article has been published in Thrombosis Journal 2021 19:49

  24. Coagulopathy is the major cause of mortality and morbidity throughout the world. Globally, about 26–45% of healthy people have a history of bleeding symptoms, which may be a result of thrombocytopenia, factor ...

    Authors: Melak Aynalem, Elias Shiferaw, Yemataw Gelaw and Bamlaku Enawgaw
    Citation: Thrombosis Journal 2021 19:36
    Content type: Research Published on:

  25. The incidence of pulmonary thromboembolism is high in SARS-CoV-2 patients admitted to the Intensive Care. Elevated biomarkers of coagulation (fibrinogen and D-dimer) and inflammation (c-reactive protein (CRP) ...

    Authors: Mark M. G. Mulder, LIoyd Brandts, Renée A. G. Brüggemann, Marcel Koelmann, Alexander S. Streng, Renske H. Olie, Hester A. Gietema, Henri M. H. Spronk, Iwan C. C. van der Horst, Jan-Willem E. M. Sels, Joachim E. Wildberger, Sander M. J. van Kuijk, Ronny M. Schnabel, Hugo ten Cate, Yvonne M. C. Henskens and Bas C. T. van Bussel
    Citation: Thrombosis Journal 2021 19:35
    Content type: Research Published on:

  26. Enoxaparin is an anticoagulant that falls in the class of medications called low molecular weight heparins (LMWHs), and is used to prevent or treat patients with deep vein thrombosis (DVT) and pulmonary emboli...

    Authors: Tao Xiang and Ming Cheng
    Citation: Thrombosis Journal 2021 19:34
    Content type: Case report Published on:

  27. Dual antiplatelet therapy can reduce coronary thrombosis and improve the prognosis in patients with acute coronary syndrome (ACS). However, there was limited prognostic information about fibrinolytic dysregula...

    Authors: Huaibin Wan, Xin Fan, Zhihao Wu, Zhenbang Lie, Daqiang Li and Shaohui Su
    Citation: Thrombosis Journal 2021 19:33
    Content type: Research Published on:

  29. COVID-19 can induce thrombotic disease both in the venous and arterial circulations, as a result of inflammation, platelet activation, endothelial dysfunction, and stasis. Although several studies have describ...

    Authors: Ehsan Aghaei Moghadam, Shima Mahmoudi, Alieh Safari Sharari, Mehrnoush Afsharipour, Mojtaba Gorji, Amene Navaeian, Azin Ghamari and Setareh Mamishi
    Citation: Thrombosis Journal 2021 19:31
    Content type: Case report Published on:

  30. Associations between D-dimer and outcomes of patients with acute coronary syndromes (ACS) remain controversial. This study aimed to investigate the prognostic value of D-dimer in ACS patients treated by percut...

    Authors: Runzhen Chen, Chen Liu, Peng Zhou, Yu Tan, Zhaoxue Sheng, Jiannan Li, Jinying Zhou, Yi Chen, Li Song, Hanjun Zhao and Hongbing Yan
    Citation: Thrombosis Journal 2021 19:30
    Content type: Research Published on:

  31. Platelet count can be altered in various diseases and treatments and measuring it may provide better insight into the expected outcome. So far, quantification of platelet count is done within laboratory condit...

    Authors: Magdolna Nagy, Sepanta Fazaeli, René van Oerle, Hugo ten Cate, Marcel Schemmann, John Sherry, Gillian Kelleher and Henri M. H. Spronk
    Citation: Thrombosis Journal 2021 19:29
    Content type: Research Published on:

  32. For patients taking warfarin and undergoing pacemaker or implantable cardioverter-defibrillator surgery, clinical evidence and guidelines support continuation of warfarin therapy, as opposed to interruption of...

    Authors: Andrew Kei-Yan Ng, Pauline Yeung Ng, Eva Wai-Ying Tam, Chung-Wah Siu and Katherine Fan
    Citation: Thrombosis Journal 2021 19:28
    Content type: Research Published on:

  33. Sphingomyelin (SM) is an essential component of biological lipid rafts, and it plays an indispensable role in maintaining plasma membrane stability and in mediating signal transduction. The ultimate biosynthes...

    Authors: Yifan Guo, Lin Chang, Ge Zhang, Zhanyan Gao, Hao Lin, Yuting Zhang, Liang Hu, She Chen, Bing Fan, Si Zhang and Ruyi Xue
    Citation: Thrombosis Journal 2021 19:27
    Content type: Research Published on:

  34. Coronavirus disease (COVID-19) pneumonitis associated with severe respiratory failure has a high mortality rate. Based on recent reports, the most severely ill patients present with coagulopathy, and dissemina...

    Authors: Fumihiro Ogawa, Yasufumi Oi, Kento Nakajima, Reo Matsumura, Tomoki Nakagawa, Takao Miyagawa, Takeru Abe and Ichiro Takeuchi
    Citation: Thrombosis Journal 2021 19:26
    Content type: Case report Published on:

  36. The purpose of this study is to elucidate the association between peripherally inserted central venous catheter (PICC) in upper extremities and lower extremity deep venous thrombosis (LEDVT) by observing the c...

    Authors: Wanli Liu, Lianxiang He, Wenjing Zeng, Liqing Yue, Jie Wei, Shuangshuang Zeng, Xiang Wang and Zhicheng Gong
    Citation: Thrombosis Journal 2021 19:24
    Content type: Research Published on:

  37. Patients on dialysis are at higher risk of major bleeding and recurrent thrombosis creating acute venous thromboembolism (VTE) treatment challenges. DOACs represent an interesting option but there are concerns...

    Authors: Guillaume Roberge and Philip Stephen Wells
    Citation: Thrombosis Journal 2021 19:23
    Content type: Case report Published on:

  38. Little is known about the difference in the severity of cardioembolic (CE) stroke between patients with paroxysmal atrial fibrillation (PAF) and persistent/permanent AF (PerAF). We assessed stroke severity in ...

    Authors: Joji Hagii, Norifumi Metoki, Shin Saito, Hiroshi Shiroto, Satoko Sasaki, Koki Takahashi, Hiroyasu Hitomi, Yoshiko Baba, Natsumi Yamada, Satoshi Seino, Takaatsu Kamada, Takamitsu Uchizawa, Taigen Nakamura, Minoru Yasujima and Hirofumi Tomita
    Citation: Thrombosis Journal 2021 19:22
    Content type: Research Published on:

  40. Antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disorder induced by antiphospholipid antibodies, which occurs exceedingly rarely in pediatric population and even more rarely reported in HIV po...

    Authors: Rong-Jing Dong, Su-Yun Lei, Jun Li, Xin-Ping Yang, Yu-Ye Li and Yun-Gui Zhang
    Citation: Thrombosis Journal 2021 19:20
    Content type: Case report Published on:

  41. Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS) is characterized by bleeding and thrombosis in patients with autoimmune diseases or infections. Paediatric LAHPS exhibits various degrees of bleeding, r...

    Authors: Atsushi Sakamoto, Masao Ogura, Atsushi Hattori, Kinji Tada, Reiko Horikawa, Hisaya Nakadate, Kimikazu Matsumoto, Keiji Nogami, Masahiro Ieko and Akira Ishiguro
    Citation: Thrombosis Journal 2021 19:19
    Content type: Case report Published on:

  42. Determination of anticoagulant therapy is of pronounced interest in emergency situations. However, routine tests do not provide sufficient insight. This study was performed to investigate the impact of anticoa...

    Authors: Philipp Groene, Daniela Wagner, Tobias Kammerer, Lars Kellert, Andreas Giebl, Steffen Massberg and Simon Thomas Schäfer
    Citation: Thrombosis Journal 2021 19:18
    Content type: Research Published on:

  43. We conducted a prospective observational study for investigating the changes in the 13th member of a disintegrin-like and metalloprotease with thrombospondin type 1 motif (ADAMTS13) and its association with th...

    Authors: Hironori Matsumoto, Jun Takeba, Kensuke Umakoshi, Satoshi Kikuchi, Muneaki Ohshita, Suguru Annen, Naoki Moriyama, Yuki Nakabayashi, Norio Sato and Mayuki Aibiki
    Citation: Thrombosis Journal 2021 19:17
    Content type: Research Published on:

  44. Polycythemia vera (PV) is characterized by red cell mass expansion in the peripheral blood and can be complicated with thrombosis, bleeding, evolution to acute myeloid leukemia (AML) or a fibrotic phase. Parox...

    Authors: Sevastianos Chatzidavid, Nefeli Giannakopoulou, Panagiotis Theodorou Diamantopoulos, Eleni Gavriilaki, Panagiota Katsiampoura, Eleftheria Lakiotaki, Stratigoula Sakellariou, Nora-Athina Viniou and Georgios Dryllis
    Citation: Thrombosis Journal 2021 19:16
    Content type: Case report Published on:

  45. COVID-19 appears to be associated with a high risk of venous thromboembolism (VTE). We aimed to systematically review and meta-analyze the risk of clinically relevant VTE in patients hospitalized for COVID-19.

    Authors: Gregoire Longchamp, Sara Manzocchi-Besson, Alban Longchamp, Marc Righini, Helia Robert-Ebadi and Marc Blondon
    Citation: Thrombosis Journal 2021 19:15
    Content type: Research Published on:

  46. Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients.

    Authors: Chuen Wen Tan, Bingwen Eugene Fan, Winnie Z. Y. Teo, Moon Ley Tung, Humaira Shafi, Dheepa Christopher, Shuwei Zheng, Wee Ming Peh, Stephrene Seok Wei Chan, Vanessa Cui Lian Chong, Christian Aledia Gallardo, Cheng Chieh Ray Chang, Li Min Ling, Jing Yuan Tan, Ken Cheah Hooi Lee, Ghee Chee Phua…
    Citation: Thrombosis Journal 2021 19:14
    Content type: Research Published on:

  47. Several observational studies have reported the rate of venous and arterial thrombotic events in patients infected with COVID-19, with conflicting results. The aim of this study was to estimate the rate of thr...

    Authors: Abdulrahman Al Raizah, Ahmed Al Askar, Naila Shaheen, Khalid Aldosari, Mohamed Alnahdi, Musumadi Luhanga, Turki Alshuaibi, Wail Bajhmoum, Khaled Alharbi, Ghaida Alsahari, Hadeel Algahtani, Eunice Alrayes, Abdulrahim Basendwah, Alia Abotaleb and Mosaad Almegren
    Citation: Thrombosis Journal 2021 19:13
    Content type: Research Published on:

  48. In patients with infectious diseases, disseminated intravascular coagulation (DIC) is often diagnosed without the fibrinogen value. The relationship between hypofibrinogenemia and outcomes of DIC in infectious...

    Authors: Kazuo Kawasugi, Hideo Wada, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba and Kohji Okamoto
    Citation: Thrombosis Journal 2021 19:12
    Content type: Research Published on:

  49. Mechanical removal of a thrombus by thrombectomy can be quite challenging. For reasons that are not fully understood, some thrombi require multiple passes to achieve successful recanalization, whereas other th...

    Authors: Senna Staessens, Olivier François, Linda Desender, Peter Vanacker, Tom Dewaele, Raf Sciot, Karen Vanhoorelbeke, Tommy Andersson and Simon F. De Meyer
    Citation: Thrombosis Journal 2021 19:11
    Content type: Case report Published on:

  50. Severe thromboembolic events are one of the major complications associated with COVID-19 infection, especially among critically ill patients. We analysed ROTEM measurements in COVID-19 patients with a severe d...

    Authors: Kristina Boss, Andreas Kribben and Bartosz Tyczynski
    Citation: Thrombosis Journal 2021 19:10
    Content type: Research Published on:
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Thrombosis Journal

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