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  1. Warfarin is the most widely used oral anticoagulant; nevertheless, dosing of warfarin is problematic for clinicians worldwide. Inter-individual variability in response to warfarin is attributed to genetic as w...

    Authors: Weam Aldiban, Yara Altawil, Samir Hussein, Majd Aljamali and Lama A. Youssef
    Citation: Thrombosis Journal 2022 20:65
    Content type: Case Report Published on:

  2. Vitamin K antagonists and different direct oral anticoagulants (DOACs) have different renal clearance rates. However, the impact of different stages of chronic renal impairment on the efficacy and safety of wa...

    Authors: Wei-Chieh Lee, Ting-Wei Liao, Hsiu-Yu Fang, Po-Jui Wu, Yen-Nan Fang, Huang-Chung Chen, Yu-Sheng Lin, Shang-Hung Chang, Ping-Yen Liu and Mien-Cheng Chen
    Citation: Thrombosis Journal 2022 20:64
    Content type: Research Published on:

  3. Neutrophil extracellular traps (NETs) may be associated with the development of thrombosis. Experimental studies have confirmed the presence of NETs in thrombi specimens and potential role of NETs in the mecha...

    Authors: Xiangbo Xu, Yuting Wu, Shixue Xu, Yue Yin, Walter Ageno, Valerio De Stefano, Qingchun Zhao and Xingshun Qi
    Citation: Thrombosis Journal 2022 20:63
    Content type: Review Published on:

  4. To estimate the incidence, risk factors, and impact on mortality and functional outcomes for early coagulopathy after the return of spontaneous circulation (ROSC) in pediatric out-of-hospital cardiac arrest (O...

    Authors: Dawei Zhou, Tong Li, Yi Lv, Dijia Wang, Rongli Zhang, Qing Lin, Chao Wang, Dong Zhao, Shuyang Fei and Wei He
    Citation: Thrombosis Journal 2022 20:62
    Content type: Research Published on:

  5. Coronavirus disease 2019 (COVID-19) has spread worldwide. Vaccination is now recommended as one of the effective countermeasures to control the pandemic or prevent the worsening of symptoms. However, its adver...

    Authors: Ryo Kaimori, Haruto Nishida, Tomohisa Uchida, Mari Tamura, Kohji Kuroki, Kumi Murata, Kinta Hatakeyama, Yoshihiko Ikeda, Kisaki Amemiya, Akira Nishizono, Tsutomu Daa and Shinjiro Mori
    Citation: Thrombosis Journal 2022 20:61
    Content type: Case Report Published on:

  6. During pregnancy and puerperium women are at high VTE risk. Current guidelines recommend dynamic VTE-risk assessment during pregnancy. Based on related RCOG-guidelines we constructed a digital VTE-risk assessm...

    Authors: Elisavet Grouzi, Abraham Pouliakis, Αnthi Aktypi, Anna Christoforidou, Paraskevi Kotsi, Georgios Αnagnostou, Aikaterini Foifa and Emmanouil Papadakis
    Citation: Thrombosis Journal 2022 20:60
    Content type: Research Published on:

  7. Rectus sheath hematoma (RSH) is a relatively uncommon cause of acute abdominal pain and can be mistaken as other surgical causes of acute abdomen. A diagnosis requires high index of suspicion especially in sus...

    Authors: Cheuk-Lik Wong and Clarence Hao-Yu So
    Citation: Thrombosis Journal 2022 20:59
    Content type: Case Report Published on:

  8. Oral anticoagulation therapy with warfarin requires frequent monitoring level of anticoagulation by the international normalized ratio (INR). In Africa, studies that explore anticoagulation control, treatment ...

    Authors: Tamrat Assefa Tadesse, Gobezie Temesgen Tegegne, Dejuma Yadeta, Legese Chelkaba and Teferi Gedif Fenta
    Citation: Thrombosis Journal 2022 20:58
    Content type: Review Published on:

  9. Portomesenteric Vein Thrombosis (PMVT) following Laparoscopic Sleeve Gastrectomy (LSG) is an uncommon but potentially debilitating complication. Catheter-Directed Thrombolysis (CDT) has an evolving role in rec...

    Authors: Ali Barah, Israa Al-Hashimi, Rahil Kassamali, Qayed Aldebyani, Omran Almokdad, Ayman Elmagdoub, Mohammed Khader, Saad U. Rehman and Ahmed Omar
    Citation: Thrombosis Journal 2022 20:57
    Content type: Case report Published on:

  10. According to several studies, ROS1 rearrangement is associated with thrombotic risk in non-small cell lung cancer (NSCLC). However, there is no clear understanding of the predictors and prognostic impact of th...

    Authors: Jiawen Yi, Huang Chen, Jie Li, Xingran Jiang, Yan Xu, Mengzhao Wang, Zheng Wang, Zhenguo Zhai, Yanhong Ren and Yuhui Zhang
    Citation: Thrombosis Journal 2022 20:56
    Content type: Research Published on:

  11. In Covid-19, anticoagulation with heparin is often administered to prevent or treat thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin treatment, caused by hepari...

    Authors: Dominik F. Draxler, Justine Brodard, Björn Zante, Stephan M. Jakob, Jan Wiegand, Johanna A. Kremer Hovinga, Anne Angelillo-Scherrer and Alicia Rovo
    Citation: Thrombosis Journal 2022 20:55
    Content type: Case Report Published on:

  12. Long non-coding RNA (lncRNA) essentially controls many physiological and pathological processes of deep vein thrombosis (DVT). Based on that, lncRNA taurine upregulated gene 1 (TUG1)-involved angiogenesis of e...

    Authors: Yaping Feng, Bo Lei, Huan Zhang, Luyuan Niu, Xiangtao Li, Xiaoyun Luo and Fuxian Zhang
    Citation: Thrombosis Journal 2022 20:54
    Content type: Research Published on:

  13. The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and a potential benefit of anticoagulation therapy has been documented for prevention of thromboembolic events. Bleeding events has also be...

    Authors: Junichi Nakamura, Ichizo Tsujino, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Satoshi Konno, Naoto Yamamoto, Hiroko Nakata, Satoshi Ikeda, Michihisa Umetsu, Shizu Aikawa, Hiroya Hayashi, Hirono Satokawa, Yoshinori Okuno, Eriko Iwata, Yoshito Ogihara…
    Citation: Thrombosis Journal 2022 20:53
    Content type: Research Published on:

  14. Isolated distal deep vein thrombosis (IDDVT), a disease frequently detected in hospitalized patients, can progress to proximal deep vein thrombosis (PDVT) and pulmonary embolism (PE). Here, we evaluated the ef...

    Authors: Xiaolin Luo, Liying Zhang, Changchun Hou, Pengda Li, Shaofa Wu, Zebi Wang, Enpu Yang, Yun Cui, Ning Sun, Yang Yu, Zhixia An, Jun Jin and Zhexue Qin
    Citation: Thrombosis Journal 2022 20:52
    Content type: Research Published on:

  16. This study aims to provide 14-year nationwide epidemiology data to evaluate the incidence ratio of APS in Taiwan and the condition of comorbidities by analyzing the National Health Insurance Research Database.

    Authors: Wei-Cheng Yao, Kam-Hang Leong, Lu-Ting Chiu, Po-Yi Chou, Li-Chih Wu, Chih-Yu Chou, Chien-Feng Kuo and Shin-Yi Tsai
    Citation: Thrombosis Journal 2022 20:50
    Content type: Research Published on:

  17. Authors: Hirotaka Mori, Yuki Kataoka, Kayo Harada-Shirado, Noriaki Kawano, Mineji Hayakawa, Yoshinobu Seki, Toshimasa Uchiyama, Kazuma Yamakawa, Hiroyasu Ishikura, Yuhei Irie, Kenji Nishio, Noritaka Yada, Kohji Okamoto, Shingo Yamada and Takayuki Ikezoe
    Citation: Thrombosis Journal 2022 20:49
    Content type: Correction Published on:

    The original article was published in Thrombosis Journal 2022 20:33

  18. SARS-CoV-2 infections are suspected to trigger the coagulation system through various pathways leading to a high incidence of thromboembolic complications, hypercoagulation and impaired fibrinolytic capacity w...

    Authors: Lars Heubner, Marvin Greiner, Oliver Vicent, Jan Beyer-Westendorf, Oliver Tiebel, Ute Scholz, Andreas Güldner, Martin Mirus, Dietmar Fries, Thea Koch and Peter Markus Spieth
    Citation: Thrombosis Journal 2022 20:48
    Content type: Research Published on:

  19. Thrombosis in patients with thrombocytopenia has several risk factors, both disease-related and treatment-associated. Recently, COVID-19 infection was recognized as an additional risk factor, further complicat...

    Authors: Alessandro Bosi, Wilma Barcellini and Bruno Fattizzo
    Citation: Thrombosis Journal 2022 20:46
    Content type: Case Report Published on:

    The Correction to this article has been published in Thrombosis Journal 2022 20:51

  20. Previous studies demonstrate a reduced risk of thrombosis and mortality with anticoagulant treatment in patients with COVID-19 than in those without anticoagulation treatment. However, an open question regardi...

    Authors: Hong Duo, Yahui Li, Yujie Sun, Liang Wei, Ziqing Wang, Fang Fang, Yuxin Zhong, Jiao Huang, Linjie Luo, Zhiyong Peng and Huaqin Pan
    Citation: Thrombosis Journal 2022 20:47
    Content type: Research Published on:

  21. Some conventional vaccines have been recognized as a cause of secondary immune thrombocytopenia (ITP). According to recent publications, mRNA vaccines are probably associated with an increased risk of ITP.

    Authors: Marc Weiner, Robert Rodriguez-Vigouroux, Stavroula Masouridi-Levrat and Kaveh Samii
    Citation: Thrombosis Journal 2022 20:45
    Content type: Case Report Published on:

  22. Cardiovascular diseases are the leading cause of death worldwide. Ticagrelor is an oral antiplatelet drug used in acute coronary syndrome. Although generic drugs are approved for their bioequivalence to the or...

    Authors: Bassem Zarif, Lamyaa Soliman, Nirmeen A. Sabry and Eman Said
    Citation: Thrombosis Journal 2022 20:44
    Content type: Research Published on:

  23. Venous thromboembolism (VTE) is a common postoperative complication in general thoracic surgery, but the incidence of patients undergoing surgery for bronchiectasis was not known. The purpose of our study was ...

    Authors: Qingshan Chen, YongSheng Cai, Zhirong Zhang, Honghong Dong, Jinbai Miao, Hui Li and Bin Hu
    Citation: Thrombosis Journal 2022 20:43
    Content type: Research Published on:

  24. The number of patients treated with extracorporeal membrane oxygenation (ECMO) devices is increasing. Anticoagulation therapy is crucial to prevent thrombosis during ECMO therapy. Predominantly, heparin has be...

    Authors: René M’Pembele, Sebastian Roth, Aljoscha Metzger, Anthony Nucaro, Alexandra Stroda, Amin Polzin, Markus W. Hollmann, Giovanna Lurati Buse and Ragnar Huhn
    Citation: Thrombosis Journal 2022 20:42
    Content type: Research Published on:

  25. The association between gastrointestinal (GI) cancer and a high incidence of venous thromboembolism (VTE) is well known. Previous randomized controlled studies demonstrated that direct oral anticoagulants (DOA...

    Authors: Tarinee Rungjirajittranon, Weerapat Owattanapanich, Yingyong Chinthammitr, Theera Ruchutrakool and Bundarika Suwanawiboon
    Citation: Thrombosis Journal 2022 20:41
    Content type: Research Published on:

  26. The detection of direct oral anticoagulants (DOACs) is still challenging but important in emergency patients. We recently demonstrated that modified thromboelastometry can detect rivaroxaban and dabigatran. Da...

    Authors: Philipp Groene, Jennifer Butte, Sarah Thaler, Klaus Görlinger and Simon T. Schäfer
    Citation: Thrombosis Journal 2022 20:40
    Content type: Research Published on:

  27. Adrenal hemorrhage (AH) is a rare condition that can result in a life-threatening medical emergency. This medical condition could be caused by several underlying factors, one of which is the use of anticoagula...

    Authors: Elahe Sheklabadi, Yasaman Sharifi, Mahdi Tabarraee, Seyed Saeed Tamehrizadeh, Parham Rabiee and Farzad Hadaegh
    Citation: Thrombosis Journal 2022 20:39
    Content type: Case Report Published on:

  28. ChAdOx1 nCoV-19 (AstraZeneca) and Ad26COV2.S (Johnson & Johnson/Janssen) adenoviral vector vaccines have been associated with vaccine-induced immune thrombotic thrombocytopenia (VITT). Arterial thrombosis and ...

    Authors: Guillaume Roberge, Benoit Côté, Anthony Calabrino, Nathalie Gilbert and Nathalie Gagnon
    Citation: Thrombosis Journal 2022 20:38
    Content type: Case Report Published on:

  29. Appropriate and timely anticoagulant therapy with vitamin K antagonists (VKAs) or non-vitamin K oral antagonists (NOACs) is essential for stroke prevention in non-valvular atrial fibrillation (NVAF). Comparati...

    Authors: Christopher Hohmann, Magnus Lutz, Sheila Vignali, Kathrin Borchert, Karolin Seidel, Sebastian Braun, Stephan Baldus and Michael Näbauer
    Citation: Thrombosis Journal 2022 20:37
    Content type: Research Published on:

  30. The anti-coagulation protocol of patients with hemorrhage risk primary disease who need extracorporeal membrane oxygenation (ECMO) supported is controversial. This study evaluated the feasibility of a new anti...

    Authors: Yang-Chao Zhao, Xi Zhao, Guo-Wei Fu, Ming-Jun Huang, Xing-Xing Li, Qian-Qian Sun, Ya-Bai Kan, Jun Li, Shi-Lei Wang, Wen-Tao Ma, Qin-Fu Xu, Qi-Long Liu and Hong-Bin Li
    Citation: Thrombosis Journal 2022 20:36
    Content type: Research Published on:

  31. Endovascular thrombectomy (EVT) is an effective therapy in acute ischemic stroke (AIS) with large vessel occlusion, especially for those who are unsuitable for intravenous thrombolysis. However, the safety and...

    Authors: Jia-Hung Chen, Chien-Tai Hong, Chen-Chih Chung, Yi-Chun Kuan and Lung Chan
    Citation: Thrombosis Journal 2022 20:35
    Content type: Research Published on:

  32. Pulmonary embolism (PE) without overt deep vein thrombosis (DVT) was common in hospitalized coronavirus-induced disease (COVID)-19 patients and represented a diagnostic, prognostic, and therapeutic challenge. ...

    Authors: Bruno Bais, Emanuela Sozio, Daniele De Silvestri, Stefano Volpetti, Maria Elena Zannier, Carla Filì, Flavio Bassi, Lucia Alcaro, Marco Cotrufo, Alberto Pagotto, Alessandro Giacinta, Vincenzo Patruno, Andrea Da Porto, Rodolfo Sbrojavacca, Francesco Curcio, Carlo Tascini…
    Citation: Thrombosis Journal 2022 20:34
    Content type: Research Published on:

  33. We compared the prognostic value of plasma high mobility group box 1 protein (HMGB1) and histone H3 levels with the International Society on Thrombosis and Haemostasis (ISTH) disseminated intravascular coagula...

    Authors: Hirotaka Mori, Yuki Kataoka, Kayo Harada-Shirado, Noriaki Kawano, Mineji Hayakawa, Yoshinobu Seki, Toshimasa Uchiyama, Kazuma Yamakawa, Hiroyasu Ishikura, Yuhei Irie, Kenji Nishio, Noritaka Yada, Kohji Okamoto, Shingo Yamada and Takayuki Ikezoe
    Citation: Thrombosis Journal 2022 20:33
    Content type: Research Published on:

    The Correction to this article has been published in Thrombosis Journal 2022 20:49

  34. The current study aims to identify the relationships between coagulation factors and plasma thrombin generation in a large population-based study by comparing individuals with a history of arterial or venous t...

    Authors: Pauline C. S. van Paridon, Marina Panova-Noeva, Rene van Oerle, Andreas Schulz, Jürgen H. Prochaska, Natalie Arnold, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Thomas Münzel, Karl J. Lackner, Hugo ten Cate, Philipp S. Wild and Henri M. H. Spronk
    Citation: Thrombosis Journal 2022 20:32
    Content type: Research Published on:

  35. For stroke prevention in patients with atrial fibrillation (AF), direct oral anticoagulants (DOACs) have been increasingly prescribed instead of vitamin-K-antagonists (VKA). For some patients a lower dosage of...

    Authors: Lisette Warkentin, Susann Hueber, Barthold Deiters, Florian Klohn and Thomas Kühlein
    Citation: Thrombosis Journal 2022 20:31
    Content type: Research Published on:

  36. Blood flow-induced shear stress affects platelet participation in coagulation and thrombin generation. We aimed to develop an in vivo model to characterize thrombin generation rates under flow.

    Authors: Wei Yin, Andrew Dimatteo, Andrew Kumpfbeck, Stephen Leung, Marina Fandaros, Bryan Musmacker, David A. Rubenstein and Mary D. Frame
    Citation: Thrombosis Journal 2022 20:30
    Content type: Research Published on:

  37. Supplementation with antithrombin (AT) concentrates is now common in the treatment of congenital and acquired AT deficiency. However, there is no established consensus on the target and timing of supplementati...

    Authors: Takumi Tsuchida, Mineji Hayakawa, Shota Kawahara and Osamu Kumano
    Citation: Thrombosis Journal 2022 20:29
    Content type: Research Published on:

  38. Acquired hemophilia A (AHA) is a rare autoimmune disease characterized by bleeding events. Recombinant activated factor VII (rFVIIa) is a first-line bypassing agent, which is effective against clinically signi...

    Authors: Hiroki Hosoi, Yuina Akagi, Toshiki Mushino, Masahiro Takeyama, Naoto Minoura, Takayuki Hiroi, Yoshiaki Furuya, Masaya Morimoto, Shogo Murata, Shinobu Tamura and Takashi Sonoki
    Citation: Thrombosis Journal 2022 20:28
    Content type: Case Report Published on:

  39. High incidence of deep vein thrombosis (DVT) has been observed in patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 and those by bacterial pneumonia. However, the differences of incid...

    Authors: Na Cui, Chunguo Jiang, Chenlu Yang, Liming Zhang and Xiaokai Feng
    Citation: Thrombosis Journal 2022 20:27
    Content type: Research Published on:

  40. Renal function is associated with prognoses for acute pulmonary embolism (PE).

    Authors: Dingyi Wang, Guohui Fan, Jieping Lei, Yuanhua Yang, Xiaomao Xu, Yingqun Ji, Qun Yi, Hong Chen, Xiaoyun Hu, Zhihong Liu, Yimin Mao, Jie Zhang, Juhong Shi, Zhu Zhang, Sinan Wu, Xincao Tao…
    Citation: Thrombosis Journal 2022 20:26
    Content type: Research Published on:

  41. The benefit of apixaban to reduce stroke risk in morbidly obese patients with nonvalvular atrial fibrillation (AF) is still undetermined. The International Society of Thrombosis and Hemostasis recommends avoid...

    Authors: Khalid Al Sulaiman, Hisham A. Badreldin, Ghazwa B. Korayem, Abeer A. Alenazi, Faisal Alsuwayyid, Abdulrahman Alrashidi, Mohammed Alhijris, Faisal Almutairi, Fahad Alharthi, Ramesh Vishwakarma, Omar Al Shaya, Abdulrahman Al Amri, Saqiba Tayyab, Abdulkareem M. Al Bekairy and Ohoud Aljuhani
    Citation: Thrombosis Journal 2022 20:25
    Content type: Research Published on:

  42. Thrombotic events cannot be completely prevented by antithrombotics, implicating a therapeutic gap due to inflammation, a not yet sufficiently addressed mechanism. Neutrophil extracellular traps (NETs) are an ...

    Authors: Yejia Chen, Xiaobo Li, Xinxin Lin, Hongbin Liang, Xuewei Liu, Xinlu Zhang, Qiuxia Zhang, Fengyun Zhou, Chen Yu, Li Lei and Jiancheng Xiu
    Citation: Thrombosis Journal 2022 20:24
    Content type: Research Published on:

  43. The fibrinolytic system plays an important role in coronary artery atherothrombosis, and especially circulating plasminogen-activator inhibitor (PAI) type 1 (PAI-1) associates with increased mortality, infarct...

    Authors: Jostein Nordeng, Svein Solheim, Sissel Åkra, Hossein Schandiz, Pavel Hoffmann, Borghild Roald, Bjørn Bendz, Harald Arnesen, Ragnhild Helseth and Ingebjørg Seljeflot
    Citation: Thrombosis Journal 2022 20:23
    Content type: Research Published on:

  44. Venous thromboembolism (VTE) is a major complication in patients with malignant tumors and orthopedic disorders. Although it is known that patients undergoing surgery for malignant musculoskeletal tumor are at...

    Authors: Kenta Hayashida, Yusuke Kawabata, Keiju Saito, Shintaro Fujita, Hyonmin Choe, Ikuma Kato, Masanobu Takeyama and Yutaka Inaba
    Citation: Thrombosis Journal 2022 20:22
    Content type: Research Published on:

  45. Despite strong antiplatelet therapy with ticagrelor, serious ischemic events still occur in patients with acute coronary syndrome (ACS). The predictability of platelet reactivity to the residual risk of ischem...

    Authors: Yuting Zou, Yuyan Wang, Yangxun Wu, Shizhao Zhang, Haiping Liu and Tong Yin
    Citation: Thrombosis Journal 2022 20:21
    Content type: Research Published on:

  46. Lymphomas are characterized by elevated synthesis of inflammatory soluble mediators that could trigger the development of venous thromboembolism (VTE). However, data on the relationship between specific immune...

    Authors: Vladimir Otasevic, Biljana Mihaljevic, Natasa Milic, Dejana Stanisavljevic, Vojin Vukovic, Kristina Tomic, Jawed Fareed and Darko Antic
    Citation: Thrombosis Journal 2022 20:20
    Content type: Research Published on:

  47. High on-treatment platelet reactivity (HTPR) remains a major problem in the acute management of ST-elevation myocardial infarction (STEMI), leading to higher rates of stent thrombosis and mortality. We aimed t...

    Authors: Georg Gelbenegger, Juergen Grafeneder, Gloria M. Gager, Jolanta M. Siller-Matula, Michael Schwameis, Bernd Jilma and Christian Schoergenhofer
    Citation: Thrombosis Journal 2022 20:19
    Content type: Research Published on:

  48. An increase in the incidence of central venous catheter (CVC)-related thrombosis (CRT) has been reported in pediatric intensive care patients over the past decade. Risk factors for the development of CRT are n...

    Authors: Haomin Li, Yang Lu, Xian Zeng, Yuqing Feng, Cangcang Fu, Huilong Duan, Qiang Shu and Jihua Zhu
    Citation: Thrombosis Journal 2022 20:18
    Content type: Research Published on:

  49. Tranexamic acid (TXA) is an antifibrinolytic agent frequently used in elective surgery to reduce blood loss. We recently found it also acts as a potent immune-modulator in patients undergoing cardiac surgery.

    Authors: Dominik F. Draxler, Gryselda Hanafi, Saffanah Zahra, Fiona McCutcheon, Heidi Ho, Charithani B. Keragala, Zikou Liu, David Daly, Thomas Painter, Sophia Wallace, Magdalena Plebanski, Paul S. Myles and Robert L. Medcalf
    Citation: Thrombosis Journal 2022 20:17
    Content type: Research Published on:
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