Volume 14 Supplement 1

State of the Art 2016: Research and Review from the 9th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis


Publication of this supplement was funded by APSTH 2016. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Taipei, Taiwan

6-9 October 2016

Go to conference site.

Edited by Ming-Ching Shen, Shu-Wha Lin, Ching-Ping Tseng and Jiaan-Der Wang.

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  1. Research

    De novo mutation and somatic mosaicism of gene mutation in type 2A, 2B and 2M VWD

    Von Willebrand disease (VWD) is not uncommon in Taiwan. In type 2 or type 3 VWD hemorrhagic symptoms are severer and laboratory data relatively more distinctive. De novo mutation and somatic mosaicism of type 2 V...

    Ming-Ching Shen, Ming Chen, Gwo-Chin Ma, Shun-Ping Chang, Ching-Yeh Lin, Bo-Do Lin and Han-Ni Hsieh

    Thrombosis Journal 2016 14(Suppl 1):36

    Published on: 4 October 2016

  2. Research

    Characteristics of Taiwanese patients of PNH in the international PNH registry

    Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and acquired hematopoietic stem cell disease, with florid clinical presentations. Although this disease has been characterized in the western countries, its ...

    Wen-Chien Chou, Wei-Han Huang, Ming-Chung Wang, Chao-Sung Chang, Shih-Peng Yeh, Tzeon-Jye Chiou, Yeu-Chin Chen, Tseng-Hsi Lin and Ming-Ching Shen

    Thrombosis Journal 2016 14(Suppl 1):39

    Published on: 4 October 2016

  3. Review

    Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies

    Platelets are central mediators of thrombosis and hemostasis. At the site of vascular injury, platelet accumulation (i.e. adhesion and aggregation) constitutes the first wave of hemostasis. Blood coagulation, ...

    Xiaohong Ruby Xu, Naadiya Carrim, Miguel Antonio Dias Neves, Thomas McKeown, Tyler W. Stratton, Rodrigo Matos Pinto Coelho, Xi Lei, Pingguo Chen, Jianhua Xu, Xiangrong Dai, Benjamin Xiaoyi Li and Heyu Ni

    Thrombosis Journal 2016 14(Suppl 1):29

    Published on: 4 October 2016

  4. Review

    Different impact of factor VIII products on inhibitor development?

    Inhibitors are the most serious side effect of haemophilia treatment; they occur in 25–30 % of all patients with severe haemophilia A. Over the last 2 decades, conflicting data on the impact of clotting produc...

    H. Marijke van den Berg

    Thrombosis Journal 2016 14(Suppl 1):31

    Published on: 4 October 2016

  5. Review

    Aspects of prophylactic treatment of hemophilia

    Retrospective and prospective studies unambiguously show that prophylactic treatment of severe hemophilia A or B should be started as primary prophylaxis at 1–2 years’ of age and ideally before the first joint...

    Rolf Ljung

    Thrombosis Journal 2016 14(Suppl 1):30

    Published on: 4 October 2016

  6. Review

    Preimplantation genetic diagnosis of hemophilia A

    Preimplantation genetic diagnosis (PGD) is a powerful tool to tackle the transmission of monogenic inherited disorders in families carrying the diseases from generation to generation. It currently remains a ch...

    Ming Chen, Shun-Ping Chang, Gwo-Chin Ma, Wen-Hsian Lin, Hsin-Fu Chen, Shee-Uan Chen, Horng-Der Tsai, Feng-Po Tsai and Ming-Ching Shen

    Thrombosis Journal 2016 14(Suppl 1):33

    Published on: 4 October 2016

  7. Review

    Extravascular FIX and coagulation

    This review summarizes the evidence that collagen IV binding is physiologically important, and that the extravascular compartment of FIX is composed of type IV collagen. As we have previously demonstrated, 7 d...

    Darrel W. Stafford

    Thrombosis Journal 2016 14(Suppl 1):35

    Published on: 4 October 2016

  8. Review

    Current animal models of hemophilia: the state of the art

    Hemophilia is the most well-known hereditary bleeding disorder, with an incidence of one in every 5000 to 30,000 males worldwide. The disease is treated by infusion of protein products on demand and as prophyl...

    Ching-Tzu Yen, Meng-Ni Fan, Yung-Li Yang, Sheng-Chieh Chou, I-Shing Yu and Shu-Wha Lin

    Thrombosis Journal 2016 14(Suppl 1):22

    Published on: 4 October 2016

  9. Review

    Management of venous thromboembolism: an update

    Venous thromboembolism (VTE), which constitutes pulmonary embolism and deep vein thrombosis, is a common disorder associated with significant morbidity and mortality. Landmark trials have shown that direct ora...

    Siavash Piran and Sam Schulman

    Thrombosis Journal 2016 14(Suppl 1):23

    Published on: 4 October 2016

  10. Review

    Causes of venous thrombosis

    Venous thrombosis which mainly manifests as deep vein thrombosis of the leg or pulmonary embolism occurs in 1 per 1000 per year. It occurs due to interacting genetic, environmental and behavioral risk factors....

    F. R. Rosendaal

    Thrombosis Journal 2016 14(Suppl 1):24

    Published on: 4 October 2016

  11. Review

    Cancer-associated thrombosis in Asia

    Thrombosis is a common complication in cancer patients. Although the major inherited risk factors for thrombophilia are different between Asians and Caucasians, the main acquired risk factors that are associat...

    Pantep Angchaisuksiri

    Thrombosis Journal 2016 14(Suppl 1):26

    Published on: 4 October 2016

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