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  1. Timely diagnosis of disseminated intravascular coagulation (DIC) in hemophagocytic lymphohistiocytosis (HLH) patients is crucial but challenging, as HLH interferes with the results of the laboratory tests incl...

    Authors: Liqin Ling, Xunbei Huang, Chaonan Liu, Juan Liao and Jing Zhou
    Citation: Thrombosis Journal 2021 19:82
  2. COVID-19 infection is associated with a hypercoagulable state. Severe COVID-19 patients present with high plasma fibrinogen levels, continuous deposition of fibrin and the presence of microthrombi in their lun...

    Authors: Yael Lichter, Tanya Badelbayov, Irina Shalev, Reut Schvartz, Yishay Szekely, Dan Benisty, Ilana Goldiner, Maxim Kagarlyk, Keren Asraf, Ram Doolman, Efrat Luttwak, Ilya Kirgner, Irit Avivi, Nimrod Adi and Ben-Zion Katz
    Citation: Thrombosis Journal 2021 19:79
  3. This study aimed to investigate the background of patients who presented with pulmonary embolism (PE) on contrast-enhanced chest computed tomography (CT) and to explore the risk factors for PE.

    Authors: Kaoru Fujieda, Akiko Nozue, Akie Watanabe, Keiko Shi, Hiroya Itagaki, Yoshihiko Hosokawa, Keiko Nishida, Nobutaka Tasaka, Toyomi Satoh and Ken Nishide
    Citation: Thrombosis Journal 2021 19:77
  4. Venous thromboembolism (VTE) is a common complication among patients with cancer and is one of the most common causes of increased morbidity and mortality. The use of direct oral anticoagulants (DOACs) for thr...

    Authors: Norah S. Alsubaie, Shahad M. Al Rammah, Reema A. Alshouimi, Mohammed Y. Alzahrani, Majed S. Al Yami, Abdulaali R. Almutairi, Osamah M. Alfayez, Ghazwa B. Korayem and Omar A. Almohammed
    Citation: Thrombosis Journal 2021 19:76
  5. In the recent COVID19 pandemic, patients with hematological disorders were considered at high risk for severe disease. Limited data is available regarding the course of COVID19 infection in this subgroup.

    Authors: Sufana Shikdar, Azra Borogovac, Elabdallah Mohamad and Mohamad Khawandanah
    Citation: Thrombosis Journal 2021 19:75
  6. Activated protein C resistance (APCR) due to factor V Leiden (FVL) mutation (R506Q) is a major risk factor in patients with venous thromboembolism (VTE). The present study investigated the clinical manifestati...

    Authors: Vahideh Takhviji, Kazem Zibara, Asma Maleki, Ebrahim Azizi, Sanaz Hommayoun, Mohammadreza Tabatabaei, Seyed Esmaeil Ahmadi, Maral Soleymani, Omid Kiani Ghalesardi, Mina Farokhian, Afshin Davari, Pouria Paridar, Anahita Kalantari and Abbas Khosravi
    Citation: Thrombosis Journal 2021 19:74
  7. This study was aimed to determine how platelet reactivity (PR) on dual antiplatelet therapy predicts ischemic and bleeding events in patients underwent percutaneous coronary intervention (PCI).

    Authors: Jing Wang, Jing Wang, Zhou Dong, Jiazheng Ma, Jianzhen Teng, Tong Wang, Xiaofeng Zhang, Qian Gu, Zekang Ye, Inam Ullah, Chuchu Tan, Samee Abdus, Lu Shi, Xiaoxuan Gong and Chunjian Li
    Citation: Thrombosis Journal 2021 19:73
  8. The antithrombotic effect of vitamin K antagonists (VKA) depends on controlled lowering of the activity of factors (F) II and X whereas reductions in FVII and FIX play little role. PT-INR based monitoring, how...

    Authors: Pall T. Onundarson, Ragnar Palsson, Daniel M. Witt and Brynja R. Gudmundsdottir
    Citation: Thrombosis Journal 2021 19:72
  9. Coagulopathy and following massive bleeding are complications of cardiovascular surgery, particularly occurring after procedures requiring prolonged cardiopulmonary bypass (CPB). Reliable and rapid tests for c...

    Authors: Yoshie Kawahara, Kohei Ohtsuka, Kimine Tanaka, Mayumi Yamanaka, Hiroyuki Kamiya, Takayuki Kunisawa and Satoshi Fujii
    Citation: Thrombosis Journal 2021 19:70
  10. Recently, direct oral anticoagulants (DOACs) have been included in guidelines for the treatment of cancer-associated thrombosis (CAT) to be extended to suitable cancer patients. The purpose of this study was t...

    Authors: Kaidireyahan Wumaier, Wenqian Li, Naifei Chen and Jiuwei Cui
    Citation: Thrombosis Journal 2021 19:68
  11. Recently, heparin-induced thrombocytopenia (HIT) after vaccination with the vaccines manufactured by AstraZeneca and Pfizer–BioNTech has been published in the New England Journal of Medicine. These reports state ...

    Authors: Kenji Yamamoto
    Citation: Thrombosis Journal 2021 19:67
  12. This is a review article on heparin-induced thrombocytopenia, an adverse effect of heparin therapy, and vaccine-induced immune thrombotic thrombocytopenia, occurring in some patients administered certain coron...

    Authors: Payel Datta, Fuming Zhang, Jonathan S. Dordick and Robert J. Linhardt
    Citation: Thrombosis Journal 2021 19:66
  13. Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but fatal complication of the Coronavirus Disease 2019 vaccine. The many reports of VITT have mostly been in the Caucasian population. Here, ...

    Authors: Archrob Khuhapinant, Tarinee Rungjirajittranon, Bundarika Suwanawiboon, Yingyong Chinthammitr and Theera Ruchutrakool
    Citation: Thrombosis Journal 2021 19:65
  14. Protein S deficiency (PSD) is an autosomal dominant hereditary disease. In 1984, familial PSD was reported to be prone to recurrent thrombosis. Follow-up studies have shown that heterozygous protein S (PROS1) mut...

    Authors: Yan-ping Zhang, Bin Lin, Yuan-yuan Ji, Ya-nan Hu, Xin-fu Lin, Yi Tang, Jian-hui Zhang, Shao-jie Wu, Sen-lin Cai, Yan-feng Zhou, Ting Chen, Zhu-ting Fang and Jie-wei Luo
    Citation: Thrombosis Journal 2021 19:64
  15. DOAC detection is challenging in emergency situations. Here, we demonstrated recently, that modified thromboelastometric tests can reliably detect and differentiate dabigatran and rivaroxaban. However, whether...

    Authors: Simon T. Schäfer, Anne-Christine Otto, Alice-Christin Acevedo, Klaus Görlinger, Steffen Massberg, Tobias Kammerer and Philipp Groene
    Citation: Thrombosis Journal 2021 19:63
  16. Intermittent pneumatic compression (IPC) is commonly used to prevent deep vein thrombosis (DVT) during hospitalization in patients with acute stroke. However, if DVT exists at admission, IPC of the legs with D...

    Authors: Takahisa Mori, Kazuhiro Yoshioka and Yuhei Tanno
    Citation: Thrombosis Journal 2021 19:62
  17. Immune thrombocytopenia (ITP) is an autoimmune disease characterized as a low platelet count resulting from immune-mediated platelet destruction. Dimethyl fumarate (DMF) is widely applied for the treatment of ...

    Authors: Huan Tong, Yangyang Ding, Xiang Gui, Zengtian Sun, Guozhang Wang, Sixuan Zhang, Zhengqing Xu, Xiamin Wang, Xiaoqi Xu, Wen Ju, Yue Li, Zhenyu Li, Lingyu Zeng, Kailin Xu and Jianlin Qiao
    Citation: Thrombosis Journal 2021 19:61
  18. Thrombin generation (TG) assessed by Calibrated Automated Thrombogram (CAT-I) reflects the overall capacity of plasma to generate thrombin, thus evaluating the balance between the anti- and procoagulant proces...

    Authors: P. L. A. Giesen, A. J. W. Gulpen, R. van Oerle, H. ten Cate, M. Nagy and H. M. H. Spronk
    Citation: Thrombosis Journal 2021 19:60
  19. Thrombosis plays an important role in the Coronavrus Disease 2019 (COVID-19) infection-related complications such as acute respiratory distress syndrome and myocardial infarction. Multiple factors such as oxyg...

    Authors: Mahin Behzadi Fard, Samaneh Behzadi Fard, Shahin Ramazi, Amir Atashi and Zahra Eslamifar
    Citation: Thrombosis Journal 2021 19:59
  20. Previous studies have shown conflicting results regarding the influence of cardiovascular risk-factors on venous thromboembolism. This study aimed to determine if these risk-factors, i.e. physical activity, sm...

    Authors: C. J. MacDonald, A. L. Madika, M. Lajous, M. Canonico, A. Fournier and M. C. Boutron-Ruault
    Citation: Thrombosis Journal 2021 19:58
  21. The coronavirus disease (COVID-19) pandemic has led to an unprecedented worldwide burden of disease. However, little is known of the longer-term implications and consequences of COVID-19. One of these may be a...

    Authors: Rajiv Advani, Torbjørn Austveg Strømsnes, Espen Stjernstrøm and Sebastian T. Lugg
    Citation: Thrombosis Journal 2021 19:57
  22. Coronavirus disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure is associated with high mortality. The pathogenesis of COVID-19 is associated with microembolism or microvascular endo...

    Authors: Fumihiro Ogawa, Yasufumi Oi, Kento Nakajima, Reo Matsumura, Tomoki Nakagawa, Takao Miyagawa, Kazuya Sakai, Ryo Saji, Hayato Taniguchi, Kohei Takahashi, Takeru Abe, Masayuki Iwashita, Mototsugu Nishii and Ichiro Takeuchi
    Citation: Thrombosis Journal 2021 19:55
  23. We review the evidence for tranexamic acid (TXA) for the treatment and prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight therapeutic areas where evidence is lacking and disc...

    Authors: Anna Ockerman, Thomas Vanassche, Melisa Garip, Christophe Vandenbriele, Matthias M Engelen, Jeroen Martens, Constantinus Politis, Reinhilde Jacobs and Peter Verhamme
    Citation: Thrombosis Journal 2021 19:54
  24. Data are limited on patient background characteristics associated with catheter ablation (CA)-related bleeding events in Japanese patients with non-valvular atrial fibrillation receiving uninterrupted periproc...

    Authors: Ichitaro Abe, Naohiko Takahashi, Yasushi Mukai, Tetsuya Kimura, Keita Yamaguchi, Atsushi Takita, Hideki Origasa and Ken Okumura
    Citation: Thrombosis Journal 2021 19:53
  25. Phlebitis, inflammation of tunica intima of venous wall, occurred in 13–56% of hospitalized patients. It is characterized by pain, erythema, swelling, palpable venous cord, and pussy discharge at catheter site...

    Authors: Mulugeta Lulie, Abilo Tadesse, Tewodros Tsegaye, Tesfaye Yesuf and Mezgebu Silamsaw
    Citation: Thrombosis Journal 2021 19:48
  26. Statins are a potential treatment for venous thromboembolism (VTE) prophylaxis complementary to conventional anticoagulants without associated bleeding complications. This study aimed to compare pro-thrombotic...

    Authors: Mohammadreza Bordbar, Renée de Mutsert, Melike Cevval, Frits R. Rosendaal, J. Wouter Jukema and Willem M. Lijfering
    Citation: Thrombosis Journal 2021 19:45
  27. Although the rate of childhood acute lymphoblastic leukemia (ALL) is increasing in Africa, there is a dearth of information on the disease and the dynamics of hemostatic parameters with therapy.

    Authors: William Osei-OWusu, David Ofosu Ntiamoah, Gordon Asare Akuffo, Selina Mintaah, Michael Owusu, Benedict Sackey, Lilian Antwi-Boateng, Ganiwu Abdul, Max Annani-Akollor, Eddie-Williams Owiredu, Alexander Yaw Debrah and Otchere Addai-Mensah
    Citation: Thrombosis Journal 2021 19:44
  28. Coronavirus disease 2019 (COVID-19) associated coagulopathy (CAC) leads to thromboembolic events in a high number of critically ill COVID-19 patients. However, specific diagnostic or therapeutic algorithms for...

    Authors: Johannes Herrmann, Quirin Notz, Tobias Schlesinger, Jan Stumpner, Markus Kredel, Magdalena Sitter, Benedikt Schmid, Peter Kranke, Harald Schulze, Patrick Meybohm and Christopher Lotz
    Citation: Thrombosis Journal 2021 19:39
  29. Deep vein thrombosis (DVT) is common in critically ill patients with Coronavirus disease 2019 (COVID-19) and may cause fatal pulmonary embolism (PE) prior to diagnosis due to subtle clinical symptoms. The aim ...

    Authors: Sarah Galien, Michael Hultström, Miklós Lipcsey, Karl Stattin, Robert Frithiof and Jacob Rosén
    Citation: Thrombosis Journal 2021 19:38
  30. There is a need for clinical outcome data of cerebral venous thrombosis (CVT) in cancer patients. We examined the recanalization, thrombosis recurrence and major bleeding during CVT treatment in a cancer exclu...

    Authors: Nadia I Abelhad, Wei Qiao, Naveen Garg and Cristhiam M. Rojas-Hernandez
    Citation: Thrombosis Journal 2021 19:37

    The Correction to this article has been published in Thrombosis Journal 2021 19:49

  31. Coagulopathy is the major cause of mortality and morbidity throughout the world. Globally, about 26–45% of healthy people have a history of bleeding symptoms, which may be a result of thrombocytopenia, factor ...

    Authors: Melak Aynalem, Elias Shiferaw, Yemataw Gelaw and Bamlaku Enawgaw
    Citation: Thrombosis Journal 2021 19:36
  32. The incidence of pulmonary thromboembolism is high in SARS-CoV-2 patients admitted to the Intensive Care. Elevated biomarkers of coagulation (fibrinogen and D-dimer) and inflammation (c-reactive protein (CRP) ...

    Authors: Mark M. G. Mulder, LIoyd Brandts, Renée A. G. Brüggemann, Marcel Koelmann, Alexander S. Streng, Renske H. Olie, Hester A. Gietema, Henri M. H. Spronk, Iwan C. C. van der Horst, Jan-Willem E. M. Sels, Joachim E. Wildberger, Sander M. J. van Kuijk, Ronny M. Schnabel, Hugo ten Cate, Yvonne M. C. Henskens and Bas C. T. van Bussel
    Citation: Thrombosis Journal 2021 19:35
  33. Enoxaparin is an anticoagulant that falls in the class of medications called low molecular weight heparins (LMWHs), and is used to prevent or treat patients with deep vein thrombosis (DVT) and pulmonary emboli...

    Authors: Tao Xiang and Ming Cheng
    Citation: Thrombosis Journal 2021 19:34
  34. Dual antiplatelet therapy can reduce coronary thrombosis and improve the prognosis in patients with acute coronary syndrome (ACS). However, there was limited prognostic information about fibrinolytic dysregula...

    Authors: Huaibin Wan, Xin Fan, Zhihao Wu, Zhenbang Lie, Daqiang Li and Shaohui Su
    Citation: Thrombosis Journal 2021 19:33
  35. COVID-19 can induce thrombotic disease both in the venous and arterial circulations, as a result of inflammation, platelet activation, endothelial dysfunction, and stasis. Although several studies have describ...

    Authors: Ehsan Aghaei Moghadam, Shima Mahmoudi, Alieh Safari Sharari, Mehrnoush Afsharipour, Mojtaba Gorji, Amene Navaeian, Azin Ghamari and Setareh Mamishi
    Citation: Thrombosis Journal 2021 19:31

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  • Thrombosis Journal is the official journal of the Asian-Pacific Society on Thrombosis and Hemostasis.

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