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  1. Unfractionated heparin and low molecular weight heparin are the most commonly used antithrombotic and thromboprophylactic agents in hospital practice. Extended out-of-hospital treatment is inconvenient in that...

    Authors: Ehud Arbit, Michael Goldberg, Isabel Gomez-Orellana and Shingai Majuru
    Citation: Thrombosis Journal 2006 4:6
    Content type: Review Published on:

  2. Platelet activation is crucial in normal hemostasis. Using a clotting system free of external tissue factor, we investigated whether activated Factor VII in combination with platelet agonists increased thrombi...

    Authors: Raul Altman, Alejandra Silvia Scazziota, Maria de Lourdes Herrera and Claudio Gonzalez
    Citation: Thrombosis Journal 2006 4:5
    Content type: Original basic research Published on:

  4. Lupus anticoagulants prolong clotting times in phospholipid-dependent coagulation tests. Lupus Ratio assays are integrated tests for lupus anticoagulants that may be based on APTT, RVVT or dPT clotting times. ...

    Authors: Eva M Jacobsen, Elin J Trettenes, Finn Wisløff and Ulrich Abildgaard
    Citation: Thrombosis Journal 2006 4:3
    Content type: Original basic research Published on:

  5. Systemic sclerosis (SSc) is an autoimmune disorder of the connective tissue characterized by widespread vascular lesions and fibrosis. Little is known so far on the activation of the hemostatic and fibrinolyti...

    Authors: Giuseppe Lippi, Alessandro Volpe, Paola Caramaschi, Gian Luca Salvagno, Martina Montagnana and Gian Cesare Guidi
    Citation: Thrombosis Journal 2006 4:2
    Content type: Original clinical investigation Published on:

  6. For patients with a normal coagulation system, who experience serious bleeding, sound evidence for recombinant activated factor VII (rFVIIa) as an effective haemostatic agent is only scarcely available so far ...

    Authors: P Eller, C Pechlaner and CJ Wiedermann
    Citation: Thrombosis Journal 2006 4:1
    Content type: Case report Published on:

  7. Natural disasters, war, and terrorist attacks, have been linked to cardiac mortality. We sought to investigate whether a major financial crisis may impact on the medical management and outcomes of acute corona...

    Authors: Enrique P Gurfinkel, Gerardo E Bozovich, Omar Dabbous, Branco Mautner and Frederick Anderson
    Citation: Thrombosis Journal 2005 3:22
    Content type: Original clinical investigation Published on:

  10. The presence of thrombi in the atherosclerotic and/or aneurysmatic aorta with peripheral arterial embolism is a common scenario. Thrombus formation in a morphologically normal aorta, however, is a rare event. ...

    Authors: Nasser M Malyar, Rolf A Janosi, Zoran Brkovic and Raimund Erbel
    Citation: Thrombosis Journal 2005 3:19
    Content type: Case report Published on:

  11. To investigate the incidence of pulmonary embolism and risk factors for this condition after obstetric and gynecologic surgery, as well as the efficacy of intermittent pneumatic compression.

    Authors: Nao Suzuki, Fumio Kataoka, Atsushi Higashiguchi, Takeshi Hirao, Sachiko Ezawa, Hiroyuki Nomura, Akiyo Tomita, Nobuyuki Susumu and Daisuke Aoki
    Citation: Thrombosis Journal 2005 3:18
    Content type: Original clinical investigation Published on:

  12. Dengue virus infected patients have high plasminogen activator inhibitor type I (PAI-1) plasma concentrations. Whether the insertion/deletion (4G/5G) polymorphism in the promotor region of the PAI-1 gene is as...

    Authors: ATA Mairuhu, TE Setiati, P Koraka, CE Hack, A Leyte, SMH Faradz, H ten Cate, DPM Brandjes, ADME Osterhaus, PH Reitsma and ECM van Gorp
    Citation: Thrombosis Journal 2005 3:17
    Content type: Original clinical investigation Published on:

  13. Thrombin generation assay was developed several years ago to mimic physiological coagulation mechanisms but it had important limitations. Thrombogram-Thrombinoscope assay using a fluorogenic substrate, allows ...

    Authors: Grigoris T Gerotziafas, François Depasse, Joël Busson, Lena Leflem, Ismail Elalamy and Meyer M Samama
    Citation: Thrombosis Journal 2005 3:16
    Content type: Original basic research Published on:

  14. Circulating procoagulant microparticles (MP) are pathogenic markers of enhanced coagulability associated to a variety of disorders and released from stimulated vascular cells. When derived from endothelial cel...

    Authors: O Morel, L Jesel, JM Freyssinet and F Toti
    Citation: Thrombosis Journal 2005 3:15
    Content type: Case report Published on:

  15. Heparin-induced thrombocytopenia (HIT) is the most important and most frequent drug-induced, immune-mediated type of thrombocytopenia. It is associated with significant morbidity and mortality if unrecognized....

    Authors: Massimo Franchini
    Citation: Thrombosis Journal 2005 3:14
    Content type: Review Published on:

  16. Many available data have suggested that hyperhomocysteinaemia, an established independent risk factor for thrombosis (arterial and venous), may be associated with an increased risk of retinal vein occlusion (R...

    Authors: Paola Ferrazzi, Pierpaolo Di Micco, Ilaria Quaglia, Lisa Simona Rossi, Alessandro Giacco Bellatorre, Giorgio Gaspari, Lidia Luciana Rota and Corrado Lodigiani
    Citation: Thrombosis Journal 2005 3:13
    Content type: Original clinical investigation Published on:

  17. The use of mouse models for the study of thrombotic disorders has gained increasing importance. Methods for measurement of coagulation activation in mice are, however, scarce. The primary aim of this study was...

    Authors: Dirkje W Sommeijer, René van Oerle, Pieter H Reitsma, Janneke J Timmerman, Joost CM Meijers, Henri MH Spronk and Hugo ten Cate
    Citation: Thrombosis Journal 2005 3:12
    Content type: Original basic research Published on:

  18. Septic thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgic...

    Authors: Patricia Volkow, Patricia Cornejo-Juárez, Ana Berta Arizpe-Bravo, Jorge García-Méndez, Enrique Baltazares-Lipp and Rogelio Pérez-Padilla
    Citation: Thrombosis Journal 2005 3:11
    Content type: Case report Published on:

  19. To be fully activated platelets are dependent on two positive feedback loops; the formation of thromboxane A2 by cyclooxygenase in the platelets and the release of ADP. We wanted to evaluate the effect of aspirin...

    Authors: Catharina Borna, Eduardo Lazarowski, Catharina van Heusden, Hans Öhlin and David Erlinge
    Citation: Thrombosis Journal 2005 3:10
    Content type: Original clinical investigation Published on:

  20. Intracardiac thrombus in Behçet's disease is an extremely rare manifestation. We report two such cases. A 20-year-old man presented with dyspnoea, cough and haemoptysis. Right heart thrombus associated with pu...

    Authors: Sonia Hammami, Silvia Mahjoub, Khaldoun Ben-Hamda, Radhia Brahem, Habib Gamra and Mohamed Ben Farhat
    Citation: Thrombosis Journal 2005 3:9
    Content type: Case report Published on:

  21. Little information is available from community-based long-term VTE cohort studies to compare the absolute thrombosis risk of established clinical and genetic risk factors.

    Authors: Michael Spannagl, Lothar AJ Heinemann, Thai DoMinh, Anita Assmann, Wolfgang Schramm and Rolf Schürmann
    Citation: Thrombosis Journal 2005 3:8
    Content type: Review Published on:

  23. We report on a 14 year old boy who presented with the symptoms abdominal pain, fever and proteinuria. A hematoma in the region of the right pararenal space was diagnosed. Prothrombin time and activated partial...

    Authors: Patrick Gerner, Michael Heldmann, Peter Borusiak, Vladimir Bures and Stefan Wirth
    Citation: Thrombosis Journal 2005 3:6
    Content type: Case report Published on:

  24. Community-based cohort studies are not available that evaluated the predictive power of both clinical and genetic risk factors for venous thromboembolism (VTE). There is, however, clinical need to forecast the li...

    Authors: Lothar AJ Heinemann, Thai DoMinh, Anita Assmann, Wolfgang Schramm, Rolf Schürmann, Jan Hilpert and Michael Spannagl
    Citation: Thrombosis Journal 2005 3:5
    Content type: Original clinical investigation Published on:

  25. With the growing use of low-molecular-weight heparins (LMWH) for the treatment and prevention of venous thromboembolism (VTE), it is important to provide an evidence-based comparison with unfractionated hepari...

    Authors: Charles FS Locke, John Dooley and Jonathan Gerber
    Citation: Thrombosis Journal 2005 3:4
    Content type: Review Published on:

  26. It is well described that diabetes mellitus is a hypercoagulable state. It is also known that patients with renal dysfunction have impaired platelet aggregation and function. It is not well described how renal...

    Authors: Donald F Brophy, rika J Martin, Todd WB Gehr and Marcus E Carr Jr
    Citation: Thrombosis Journal 2005 3:3
    Content type: Original clinical investigation Published on:

  27. Fibrin D-dimer levels have been advocated as an useful clinical marker of thrombogenesis.

    Authors: Eleni Hatzinikolaou-Kotsakou, Zafirios Kartasis, Dimitrios Tziakas, Dimitrios Stakos, Athanasios Hotidis, Georgios Chalikias, Georgios Bourikas and Dimitrios I Hatseras
    Citation: Thrombosis Journal 2005 3:2
    Content type: Original clinical investigation Published on:

  28. The use of antithrombotic agents and falls are independently associated with an increased risk of hemorrhagic injury. However, few studies have delineated the risk of fall-related hemorrhagic complications in ...

    Authors: Andrew J Bond, Frank J Molnar, Marilyn Li, Marlene Mackey and Malcolm Man-Son-Hing
    Citation: Thrombosis Journal 2005 3:1
    Content type: Original clinical investigation Published on:

  31. Some haematological diseases are associated to an increased risk of thromboembolic events. We report a case of paroxysmal nocturnal haemoglobinuria (PNH) in which a cerebrovascular event represented the first ...

    Authors: Gianluca Granata, Tiziana Izzo, Pierpaolo Di Micco, Barbara Bonamassa, Giampiero Castaldo, Vito Giuseppe Viggiano, Ugo Picillo, Giuseppe Castaldo and Alferio Niglio
    Citation: Thrombosis Journal 2004 2:10
    Content type: Case report Published on:

  33. A 42 year-old male former semi-professional soccer player sustained a right lower extremity popliteal contusion during a soccer game. He was clinically diagnosed with a possible traumatic deep vein thrombosis ...

    Authors: Paul S Echlin, Ross EG Upshur, Douglas B McKeag and Harsha P Jayatilake
    Citation: Thrombosis Journal 2004 2:8
    Content type: Case report Published on:

  34. Endothelial cell dysfunction may be implicated in the development of multiple organ failure (MOF) by a number of mechanisms. Among these, altered fibrinolysis promotes fibrin deposition, which may create micro...

    Authors: Karim Zouaoui Boudjeltia, Michael Piagnerelli, Dany Brohée, Michel Guillaume, Philippe Cauchie, Jean-Louis Vincent, Claude Remacle, Yves Bouckaert and Michel Vanhaeverbeek
    Citation: Thrombosis Journal 2004 2:7
    Content type: Original clinical investigation Published on:

  35. In the general population, mild renal impairment is associated with increases risk for coronary artery disease and stroke, suggesting that cardiovascular disease begins to develop early in the natural history ...

    Authors: Enrique P Gurfinkel, Cecilia Perel and Gonzalo Pombo
    Citation: Thrombosis Journal 2004 2:6
    Content type: Original clinical investigation Published on:

  37. The inflammatory response, initiated by neutrophil and monocyte adhesion to endothelial cells, is important in the pathogenesis of acute coronary syndromes. Platelets play an important role in inflammatory pro...

    Authors: Ertugrul Ercan, Huseyin Bozdemir, Istemihan Tengiz, Cevad Sekuri, Emil Aliyev, Azem Akilli and Mustafa Akin
    Citation: Thrombosis Journal 2004 2:4
    Content type: Original clinical investigation Published on:

  38. Consensus Conferences and Guidelines for deep vein thrombosis prophylaxis have been published, which recommend the use of prophylactic heparins in patients with risk of venous thromboembolism (VTE). The aim of...

    Authors: Antonio Vallano, Josep Maria Arnau, Gaietà Permanyer Miralda and Jaume Pérez-Bartolí
    Citation: Thrombosis Journal 2004 2:3
    Content type: Original clinical investigation Published on:

  41. International Normalized Ratio (INR) is a world-wide routinely used factor in the monitoring of oral anticoagulation treatment (OAT). However, it was reported that other factors, e. g. factor II, may even bett...

    Authors: Cezary Watala, Jacek Golanski and Przemyslaw Kardas
    Citation: Thrombosis Journal 2003 1:7
    Content type: Original basic research Published on:

  42. Tissue factor (TF), expressed in endothelial cells (ECs) and enriched in human atherosclerotic lesions, acts as a critical initiator of blood coagulation in acute coronary syndrome. Basic fibroblast growth fac...

    Authors: Takeaki Kaneko, Satoshi Fujii, Akio Matsumoto, Daisuke Goto, Naomasa Makita, Junichi Hamada, Tetsuya Moriuchi and Akira Kitabatake
    Citation: Thrombosis Journal 2003 1:6
    Content type: Original basic research Published on:

  43. Conflicting results have been reported regarding the association of gene polymorphisms in the renin-angiotensin system (RAS) with different aspects of coronary artery disease (CAD), such as myocardial infarcti...

    Authors: Nicolas Lamblin, Xavier Hermant, Jean-Marc Lablanche, Nicole Helbecque, Philippe Amouyel and Christophe Bauters
    Citation: Thrombosis Journal 2003 1:5
    Content type: Original clinical investigation Published on:

  45. In spite of using heparin-coated extracorporeal circuits, cardiopulmonary bypass (CPB) is still associated with an extensive thrombin generation, which is only partially suppressed by the use of high dosages o...

    Authors: Patrick W Weerwind, Theo Lindhout, Nicole EH Caberg and Dick S de Jong
    Citation: Thrombosis Journal 2003 1:3
    Content type: Original clinical investigation Published on:

  47. An excessive perioperative blood loss, that requires transfusion of blood products, sometimes occurs in patients undergoing cardiopulmonary bypass for cardiac surgery. Blood loss and transfusion requirements i...

    Authors: Domenico Prisco and Rita Paniccia
    Citation: Thrombosis Journal 2003 1:1
    Content type: Review Published on:
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